Inhibition of cytotoxic fibril formation of α-synuclein and human insulin by Silymarin from the Silybum marianum.

Silymarin (SIL), the extract obtained from the seeds of milk thistle (Silybum marianum), contains several flavonolignans with a broad range of therapeutic properties such as antioxidant, anti-inflammatory, and neuroprotective effects. Despite several studies indicating the neuroprotective effects of...

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Bibliographic Details
Main Authors: Beitollah Moosakhani, Mahshid Taleb, Zahra Mahmoudi Eshkaftaki, Nasser Nikfarjam, Azam Serajian, Mohammad Bagher Shahsavani, Ali Akbar Meratan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0320283
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