A wireless multi-channel recording system for freely behaving mice and rats.
To understand the neural basis of behavior, it is necessary to record brain activity in freely moving animals. Advances in implantable multi-electrode array technology have enabled researchers to record the activity of neuronal ensembles from multiple brain regions. The full potential of this approa...
Saved in:
| Main Authors: | , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2011-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0022033&type=printable |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850224453865177088 |
|---|---|
| author | David Fan Dylan Rich Tahl Holtzman Patrick Ruther Jeffrey W Dalley Alberto Lopez Mark A Rossi Joseph W Barter Daniel Salas-Meza Stanislav Herwik Tobias Holzhammer James Morizio Henry H Yin |
| author_facet | David Fan Dylan Rich Tahl Holtzman Patrick Ruther Jeffrey W Dalley Alberto Lopez Mark A Rossi Joseph W Barter Daniel Salas-Meza Stanislav Herwik Tobias Holzhammer James Morizio Henry H Yin |
| author_sort | David Fan |
| collection | DOAJ |
| description | To understand the neural basis of behavior, it is necessary to record brain activity in freely moving animals. Advances in implantable multi-electrode array technology have enabled researchers to record the activity of neuronal ensembles from multiple brain regions. The full potential of this approach is currently limited by reliance on cable tethers, with bundles of wires connecting the implanted electrodes to the data acquisition system while impeding the natural behavior of the animal. To overcome these limitations, here we introduce a multi-channel wireless headstage system designed for small animals such as rats and mice. A variety of single unit and local field potential signals were recorded from the dorsal striatum and substantia nigra in mice and the ventral striatum and prefrontal cortex simultaneously in rats. This wireless system could be interfaced with commercially available data acquisition systems, and the signals obtained were comparable in quality to those acquired using cable tethers. On account of its small size, light weight, and rechargeable battery, this wireless headstage system is suitable for studying the neural basis of natural behavior, eliminating the need for wires, commutators, and other limitations associated with traditional tethered recording systems. |
| format | Article |
| id | doaj-art-eacd11f19ec84e86b59a51b6ecb83fc3 |
| institution | OA Journals |
| issn | 1932-6203 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj-art-eacd11f19ec84e86b59a51b6ecb83fc32025-08-20T02:05:36ZengPublic Library of Science (PLoS)PLoS ONE1932-62032011-01-0167e2203310.1371/journal.pone.0022033A wireless multi-channel recording system for freely behaving mice and rats.David FanDylan RichTahl HoltzmanPatrick RutherJeffrey W DalleyAlberto LopezMark A RossiJoseph W BarterDaniel Salas-MezaStanislav HerwikTobias HolzhammerJames MorizioHenry H YinTo understand the neural basis of behavior, it is necessary to record brain activity in freely moving animals. Advances in implantable multi-electrode array technology have enabled researchers to record the activity of neuronal ensembles from multiple brain regions. The full potential of this approach is currently limited by reliance on cable tethers, with bundles of wires connecting the implanted electrodes to the data acquisition system while impeding the natural behavior of the animal. To overcome these limitations, here we introduce a multi-channel wireless headstage system designed for small animals such as rats and mice. A variety of single unit and local field potential signals were recorded from the dorsal striatum and substantia nigra in mice and the ventral striatum and prefrontal cortex simultaneously in rats. This wireless system could be interfaced with commercially available data acquisition systems, and the signals obtained were comparable in quality to those acquired using cable tethers. On account of its small size, light weight, and rechargeable battery, this wireless headstage system is suitable for studying the neural basis of natural behavior, eliminating the need for wires, commutators, and other limitations associated with traditional tethered recording systems.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0022033&type=printable |
| spellingShingle | David Fan Dylan Rich Tahl Holtzman Patrick Ruther Jeffrey W Dalley Alberto Lopez Mark A Rossi Joseph W Barter Daniel Salas-Meza Stanislav Herwik Tobias Holzhammer James Morizio Henry H Yin A wireless multi-channel recording system for freely behaving mice and rats. PLoS ONE |
| title | A wireless multi-channel recording system for freely behaving mice and rats. |
| title_full | A wireless multi-channel recording system for freely behaving mice and rats. |
| title_fullStr | A wireless multi-channel recording system for freely behaving mice and rats. |
| title_full_unstemmed | A wireless multi-channel recording system for freely behaving mice and rats. |
| title_short | A wireless multi-channel recording system for freely behaving mice and rats. |
| title_sort | wireless multi channel recording system for freely behaving mice and rats |
| url | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0022033&type=printable |
| work_keys_str_mv | AT davidfan awirelessmultichannelrecordingsystemforfreelybehavingmiceandrats AT dylanrich awirelessmultichannelrecordingsystemforfreelybehavingmiceandrats AT tahlholtzman awirelessmultichannelrecordingsystemforfreelybehavingmiceandrats AT patrickruther awirelessmultichannelrecordingsystemforfreelybehavingmiceandrats AT jeffreywdalley awirelessmultichannelrecordingsystemforfreelybehavingmiceandrats AT albertolopez awirelessmultichannelrecordingsystemforfreelybehavingmiceandrats AT markarossi awirelessmultichannelrecordingsystemforfreelybehavingmiceandrats AT josephwbarter awirelessmultichannelrecordingsystemforfreelybehavingmiceandrats AT danielsalasmeza awirelessmultichannelrecordingsystemforfreelybehavingmiceandrats AT stanislavherwik awirelessmultichannelrecordingsystemforfreelybehavingmiceandrats AT tobiasholzhammer awirelessmultichannelrecordingsystemforfreelybehavingmiceandrats AT jamesmorizio awirelessmultichannelrecordingsystemforfreelybehavingmiceandrats AT henryhyin awirelessmultichannelrecordingsystemforfreelybehavingmiceandrats AT davidfan wirelessmultichannelrecordingsystemforfreelybehavingmiceandrats AT dylanrich wirelessmultichannelrecordingsystemforfreelybehavingmiceandrats AT tahlholtzman wirelessmultichannelrecordingsystemforfreelybehavingmiceandrats AT patrickruther wirelessmultichannelrecordingsystemforfreelybehavingmiceandrats AT jeffreywdalley wirelessmultichannelrecordingsystemforfreelybehavingmiceandrats AT albertolopez wirelessmultichannelrecordingsystemforfreelybehavingmiceandrats AT markarossi wirelessmultichannelrecordingsystemforfreelybehavingmiceandrats AT josephwbarter wirelessmultichannelrecordingsystemforfreelybehavingmiceandrats AT danielsalasmeza wirelessmultichannelrecordingsystemforfreelybehavingmiceandrats AT stanislavherwik wirelessmultichannelrecordingsystemforfreelybehavingmiceandrats AT tobiasholzhammer wirelessmultichannelrecordingsystemforfreelybehavingmiceandrats AT jamesmorizio wirelessmultichannelrecordingsystemforfreelybehavingmiceandrats AT henryhyin wirelessmultichannelrecordingsystemforfreelybehavingmiceandrats |