Prediction of suicide using web based voice recordings analyzed by artificial intelligence

Abstract The integration of machine learning (ML) and deep learning models in suicide risk assessment has advanced significantly in recent years. In this study, we utilized ML in a case-control design, we predicted completed suicides using publicly available, web-based, real-world voice data, and tr...

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Main Authors: Agnieszka Ewa Krautz, Julia Volkening, Janik Raue, Christian Otte, Simon B. Eickhoff, Eike Ahlers, Jörg Langner
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-08639-2
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author Agnieszka Ewa Krautz
Julia Volkening
Janik Raue
Christian Otte
Simon B. Eickhoff
Eike Ahlers
Jörg Langner
author_facet Agnieszka Ewa Krautz
Julia Volkening
Janik Raue
Christian Otte
Simon B. Eickhoff
Eike Ahlers
Jörg Langner
author_sort Agnieszka Ewa Krautz
collection DOAJ
description Abstract The integration of machine learning (ML) and deep learning models in suicide risk assessment has advanced significantly in recent years. In this study, we utilized ML in a case-control design, we predicted completed suicides using publicly available, web-based, real-world voice data, and treating speech as a biomarker. Our model demonstrated high accuracy in distinguishing between individuals who died by suicide and carefully matched controls achieving an area under the curve (AUC) of 0.74. This improved to an AUC of 0.85 and an accuracy of 76% when analyzing the subset of individuals who died by suicide within 12 months of the audio recording. The best predictive performance was observed with the Multilayer perceptron model, particularly when using the all Bene, Q + U Bene, and Q + U Raw feature sets—highlighting the importance of combining structured and unstructured paralinguistic features. The findings highlight the critical temporal proximity of voice biomarkers to suicide risk. The model’s robustness is further evidenced by its resilience to perturbations in the analytical pipeline. This is the first study to successfully predict actual suicidal behavior rather than surrogate markers, marking a major step forward in suicide prevention. By demonstrating that speech can serve as a non-invasive and objective biomarker for suicide risk, this research opens new avenues for diagnostic and prognostic applications.
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spelling doaj-art-eac7a319f2124fe787ad0778f273ab042025-08-20T03:45:28ZengNature PortfolioScientific Reports2045-23222025-07-0115111010.1038/s41598-025-08639-2Prediction of suicide using web based voice recordings analyzed by artificial intelligenceAgnieszka Ewa Krautz0Julia Volkening1Janik Raue2Christian Otte3Simon B. Eickhoff4Eike Ahlers5Jörg Langner6PeakProfiling GmbHPeakProfiling GmbHPeakProfiling GmbHDepartment of Psychiatry and Psychotherapy, Charité – University Hospital Berlin, Corporate Member of Free University of Berlin, Humboldt University of Berlin and Berlin Institute of Health, Campus Benjamin FranklinResearch Centre Jülich, Institute of Neuroscience and Medicine, Brain & Behaviour (INM-7)Department of Psychiatry and Psychotherapy, Charité – University Hospital Berlin, Corporate Member of Free University of Berlin, Humboldt University of Berlin and Berlin Institute of Health, Campus Benjamin FranklinPeakProfiling GmbHAbstract The integration of machine learning (ML) and deep learning models in suicide risk assessment has advanced significantly in recent years. In this study, we utilized ML in a case-control design, we predicted completed suicides using publicly available, web-based, real-world voice data, and treating speech as a biomarker. Our model demonstrated high accuracy in distinguishing between individuals who died by suicide and carefully matched controls achieving an area under the curve (AUC) of 0.74. This improved to an AUC of 0.85 and an accuracy of 76% when analyzing the subset of individuals who died by suicide within 12 months of the audio recording. The best predictive performance was observed with the Multilayer perceptron model, particularly when using the all Bene, Q + U Bene, and Q + U Raw feature sets—highlighting the importance of combining structured and unstructured paralinguistic features. The findings highlight the critical temporal proximity of voice biomarkers to suicide risk. The model’s robustness is further evidenced by its resilience to perturbations in the analytical pipeline. This is the first study to successfully predict actual suicidal behavior rather than surrogate markers, marking a major step forward in suicide prevention. By demonstrating that speech can serve as a non-invasive and objective biomarker for suicide risk, this research opens new avenues for diagnostic and prognostic applications.https://doi.org/10.1038/s41598-025-08639-2SuicideVoice biomarkerArtificial intelligenceMachine learningMental health diagnostics
spellingShingle Agnieszka Ewa Krautz
Julia Volkening
Janik Raue
Christian Otte
Simon B. Eickhoff
Eike Ahlers
Jörg Langner
Prediction of suicide using web based voice recordings analyzed by artificial intelligence
Scientific Reports
Suicide
Voice biomarker
Artificial intelligence
Machine learning
Mental health diagnostics
title Prediction of suicide using web based voice recordings analyzed by artificial intelligence
title_full Prediction of suicide using web based voice recordings analyzed by artificial intelligence
title_fullStr Prediction of suicide using web based voice recordings analyzed by artificial intelligence
title_full_unstemmed Prediction of suicide using web based voice recordings analyzed by artificial intelligence
title_short Prediction of suicide using web based voice recordings analyzed by artificial intelligence
title_sort prediction of suicide using web based voice recordings analyzed by artificial intelligence
topic Suicide
Voice biomarker
Artificial intelligence
Machine learning
Mental health diagnostics
url https://doi.org/10.1038/s41598-025-08639-2
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