Racial Disparities in Clinical Outcomes of Takotsubo Cardiomyopathy: An Analysis of the National Inpatient Sample 2006 to 2018
Background This study aimed to evaluate the impact of race on in‐hospital outcomes of Takotsubo cardiomyopathy using the National Inpatient Sample. Methods and Results We conducted a retrospective study using data from the National Inpatient Sample database 2006 to 2018. We focused on Takotsubo card...
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Wiley
2024-08-01
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| Series: | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
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| Online Access: | https://www.ahajournals.org/doi/10.1161/JAHA.124.034264 |
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| author | Chi N. Duong Quoc V. P. Bui Thomas Duong Dai Q. Phan Jan Mazur Eugene Chung Vien T. Truong |
| author_facet | Chi N. Duong Quoc V. P. Bui Thomas Duong Dai Q. Phan Jan Mazur Eugene Chung Vien T. Truong |
| author_sort | Chi N. Duong |
| collection | DOAJ |
| description | Background This study aimed to evaluate the impact of race on in‐hospital outcomes of Takotsubo cardiomyopathy using the National Inpatient Sample. Methods and Results We conducted a retrospective study using data from the National Inpatient Sample database 2006 to 2018. We focused on Takotsubo cardiomyopathy hospitalizations, excluding those with acute coronary syndrome as the primary diagnosis. Two study groups consisted of White patients or Black patients. Univariate and multivariable logistic models evaluated race's effect on death, cardiac arrest, cardiogenic shock, length of stay, while adjusting for potential confounders. The Bayesian model averaging technique was used to further elucidate the factors influencing death within each racial group. Significant differences were observed between the 2 racial groups. Black patients presented at a younger age, had a higher proportion of men, a higher burden of comorbidities, and a lower median household income compared with their White counterparts. In the univariate model, the Black cohort showed an increased risk of cardiac arrest (odds ratio, 1.45 [95% CI, 1.15–1.82]). However, the difference did not reach statistical significance in the multivariable model. Black patients also had a significantly longer hospital stay in both the univariate model (risk ratio, 1.26 [95% CI, 1.22–1.31]) and the multivariable model (risk ratio, 1.06 [95% CI, 1.04–1.07]). No significant difference in all‐cause death was observed between the racial groups. Conclusions The outcome differences between 2 racial groups in our study are likely influenced by racial disparities in demographics, comorbidities, and socioeconomic factors. Individualized care based on racial group needs is crucial in clinical practice. |
| format | Article |
| id | doaj-art-eabe8cf1d2a54fb3b711a92e5d28838f |
| institution | DOAJ |
| issn | 2047-9980 |
| language | English |
| publishDate | 2024-08-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
| spelling | doaj-art-eabe8cf1d2a54fb3b711a92e5d28838f2025-08-20T03:10:31ZengWileyJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease2047-99802024-08-01131510.1161/JAHA.124.034264Racial Disparities in Clinical Outcomes of Takotsubo Cardiomyopathy: An Analysis of the National Inpatient Sample 2006 to 2018Chi N. Duong0Quoc V. P. Bui1Thomas Duong2Dai Q. Phan3Jan Mazur4Eugene Chung5Vien T. Truong6University of Massachusetts Lowell MA USAWashington University in St. Louis, School of Medicine St. Louis MO USADepartment of Mathematics & Statistics Univ of Houston‐Downtown (UHD) Houston TX USAMien Dong Innovative Technology University Dong Nai VietnamUniversity of Cincinnati Cincinnati OH USAThe Christ Hospital Health Network Cincinnati OH USAThe Christ Hospital Health Network Cincinnati OH USABackground This study aimed to evaluate the impact of race on in‐hospital outcomes of Takotsubo cardiomyopathy using the National Inpatient Sample. Methods and Results We conducted a retrospective study using data from the National Inpatient Sample database 2006 to 2018. We focused on Takotsubo cardiomyopathy hospitalizations, excluding those with acute coronary syndrome as the primary diagnosis. Two study groups consisted of White patients or Black patients. Univariate and multivariable logistic models evaluated race's effect on death, cardiac arrest, cardiogenic shock, length of stay, while adjusting for potential confounders. The Bayesian model averaging technique was used to further elucidate the factors influencing death within each racial group. Significant differences were observed between the 2 racial groups. Black patients presented at a younger age, had a higher proportion of men, a higher burden of comorbidities, and a lower median household income compared with their White counterparts. In the univariate model, the Black cohort showed an increased risk of cardiac arrest (odds ratio, 1.45 [95% CI, 1.15–1.82]). However, the difference did not reach statistical significance in the multivariable model. Black patients also had a significantly longer hospital stay in both the univariate model (risk ratio, 1.26 [95% CI, 1.22–1.31]) and the multivariable model (risk ratio, 1.06 [95% CI, 1.04–1.07]). No significant difference in all‐cause death was observed between the racial groups. Conclusions The outcome differences between 2 racial groups in our study are likely influenced by racial disparities in demographics, comorbidities, and socioeconomic factors. Individualized care based on racial group needs is crucial in clinical practice.https://www.ahajournals.org/doi/10.1161/JAHA.124.034264Black patientsNational Inpatient SampleTakotsubo cardiomyopathyWhite patients |
| spellingShingle | Chi N. Duong Quoc V. P. Bui Thomas Duong Dai Q. Phan Jan Mazur Eugene Chung Vien T. Truong Racial Disparities in Clinical Outcomes of Takotsubo Cardiomyopathy: An Analysis of the National Inpatient Sample 2006 to 2018 Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease Black patients National Inpatient Sample Takotsubo cardiomyopathy White patients |
| title | Racial Disparities in Clinical Outcomes of Takotsubo Cardiomyopathy: An Analysis of the National Inpatient Sample 2006 to 2018 |
| title_full | Racial Disparities in Clinical Outcomes of Takotsubo Cardiomyopathy: An Analysis of the National Inpatient Sample 2006 to 2018 |
| title_fullStr | Racial Disparities in Clinical Outcomes of Takotsubo Cardiomyopathy: An Analysis of the National Inpatient Sample 2006 to 2018 |
| title_full_unstemmed | Racial Disparities in Clinical Outcomes of Takotsubo Cardiomyopathy: An Analysis of the National Inpatient Sample 2006 to 2018 |
| title_short | Racial Disparities in Clinical Outcomes of Takotsubo Cardiomyopathy: An Analysis of the National Inpatient Sample 2006 to 2018 |
| title_sort | racial disparities in clinical outcomes of takotsubo cardiomyopathy an analysis of the national inpatient sample 2006 to 2018 |
| topic | Black patients National Inpatient Sample Takotsubo cardiomyopathy White patients |
| url | https://www.ahajournals.org/doi/10.1161/JAHA.124.034264 |
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