Silica Boron Sulfonic Acid as Heterogeneous and Highly Efficient Solid Acid Catalyst For the Preparation of Hantzsch 1,4-dihydropyridines Under Solvent-Free

Silica boron sulfonic acid [SiO2–B(OSO3H)3] as an inexpensive, reusable, and Lewis and Brønsted acid catalyst was successfully synthesized, and used for the one-pot three-components synthesis of biologically active substituted Hantzsch 1,4-dihydropyridine derivatives  in the absence of solvent at 90...

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Main Authors: sami sajjadifar, Pegah Masoudi
Format: Article
Language:English
Published: University of Tehran 2019-01-01
Series:Journal of Sciences, Islamic Republic of Iran
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Online Access:https://jsciences.ut.ac.ir/article_69630_eee53c52bab9292f41c319f8bf4959b6.pdf
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author sami sajjadifar
Pegah Masoudi
author_facet sami sajjadifar
Pegah Masoudi
author_sort sami sajjadifar
collection DOAJ
description Silica boron sulfonic acid [SiO2–B(OSO3H)3] as an inexpensive, reusable, and Lewis and Brønsted acid catalyst was successfully synthesized, and used for the one-pot three-components synthesis of biologically active substituted Hantzsch 1,4-dihydropyridine derivatives  in the absence of solvent at 90ºC. Silica boron sulfonic acid is attractive and efficient, because it plays in two role as a Lewis acid (by boron atom) and also as a Brønsted acid (by OSO3H group), which can have a  better effect in reaction. The reaction was carried out under solvent-free and mild conditions. Silica boron sulfonic acid can be recovered and reused for at least five consecutive runs.
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publishDate 2019-01-01
publisher University of Tehran
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series Journal of Sciences, Islamic Republic of Iran
spelling doaj-art-eabd046d4d79433a9795f89da9e6fc7b2025-08-20T03:08:47ZengUniversity of TehranJournal of Sciences, Islamic Republic of Iran1016-11042345-69142019-01-01301334010.22059/jsciences.2019.6963069630Silica Boron Sulfonic Acid as Heterogeneous and Highly Efficient Solid Acid Catalyst For the Preparation of Hantzsch 1,4-dihydropyridines Under Solvent-Freesami sajjadifar0Pegah Masoudi1Department of Chemistry, Payame Noor University, PO BOX 19395-4697 Tehran, IranDepartment of Chemistry, Payame Noor University, PO BOX 19395-4697 Tehran, IranSilica boron sulfonic acid [SiO2–B(OSO3H)3] as an inexpensive, reusable, and Lewis and Brønsted acid catalyst was successfully synthesized, and used for the one-pot three-components synthesis of biologically active substituted Hantzsch 1,4-dihydropyridine derivatives  in the absence of solvent at 90ºC. Silica boron sulfonic acid is attractive and efficient, because it plays in two role as a Lewis acid (by boron atom) and also as a Brønsted acid (by OSO3H group), which can have a  better effect in reaction. The reaction was carried out under solvent-free and mild conditions. Silica boron sulfonic acid can be recovered and reused for at least five consecutive runs.https://jsciences.ut.ac.ir/article_69630_eee53c52bab9292f41c319f8bf4959b6.pdflewis and brønsted acidichantzsch reaction1,4-dihydropyridinesolvent-freeone-pot condensation
spellingShingle sami sajjadifar
Pegah Masoudi
Silica Boron Sulfonic Acid as Heterogeneous and Highly Efficient Solid Acid Catalyst For the Preparation of Hantzsch 1,4-dihydropyridines Under Solvent-Free
Journal of Sciences, Islamic Republic of Iran
lewis and brønsted acidic
hantzsch reaction
1,4-dihydropyridine
solvent-free
one-pot condensation
title Silica Boron Sulfonic Acid as Heterogeneous and Highly Efficient Solid Acid Catalyst For the Preparation of Hantzsch 1,4-dihydropyridines Under Solvent-Free
title_full Silica Boron Sulfonic Acid as Heterogeneous and Highly Efficient Solid Acid Catalyst For the Preparation of Hantzsch 1,4-dihydropyridines Under Solvent-Free
title_fullStr Silica Boron Sulfonic Acid as Heterogeneous and Highly Efficient Solid Acid Catalyst For the Preparation of Hantzsch 1,4-dihydropyridines Under Solvent-Free
title_full_unstemmed Silica Boron Sulfonic Acid as Heterogeneous and Highly Efficient Solid Acid Catalyst For the Preparation of Hantzsch 1,4-dihydropyridines Under Solvent-Free
title_short Silica Boron Sulfonic Acid as Heterogeneous and Highly Efficient Solid Acid Catalyst For the Preparation of Hantzsch 1,4-dihydropyridines Under Solvent-Free
title_sort silica boron sulfonic acid as heterogeneous and highly efficient solid acid catalyst for the preparation of hantzsch 1 4 dihydropyridines under solvent free
topic lewis and brønsted acidic
hantzsch reaction
1,4-dihydropyridine
solvent-free
one-pot condensation
url https://jsciences.ut.ac.ir/article_69630_eee53c52bab9292f41c319f8bf4959b6.pdf
work_keys_str_mv AT samisajjadifar silicaboronsulfonicacidasheterogeneousandhighlyefficientsolidacidcatalystforthepreparationofhantzsch14dihydropyridinesundersolventfree
AT pegahmasoudi silicaboronsulfonicacidasheterogeneousandhighlyefficientsolidacidcatalystforthepreparationofhantzsch14dihydropyridinesundersolventfree