Electro-optical Analysis of the Effects of Bacteriophages on Microbial Cells

The effect of the ФАb-Sр7 bacteriophage on the change in the electro-optical (EO) parameters of cell suspensions with respect to 14 strains of bacteria of the genus Azospirillum, 2 strains of the genus Niveispirillum, 2 strains of Escherichia coli, and 2 strains of Pseudomonas putida, as well as Aci...

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Main Authors: O. I. Guliy, O. A. Karavaeva, O. S. Larionova, S. V. Larionov, L. G. Lovtsova, K. Yu. Uskov, V. D. Bunin
Format: Article
Language:Russian
Published: LLC "Publishing House OKI" 2020-05-01
Series:Антибиотики и Химиотерапия
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Online Access:https://www.antibiotics-chemotherapy.ru/jour/article/view/64
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author O. I. Guliy
O. A. Karavaeva
O. S. Larionova
S. V. Larionov
L. G. Lovtsova
K. Yu. Uskov
V. D. Bunin
author_facet O. I. Guliy
O. A. Karavaeva
O. S. Larionova
S. V. Larionov
L. G. Lovtsova
K. Yu. Uskov
V. D. Bunin
author_sort O. I. Guliy
collection DOAJ
description The effect of the ФАb-Sр7 bacteriophage on the change in the electro-optical (EO) parameters of cell suspensions with respect to 14 strains of bacteria of the genus Azospirillum, 2 strains of the genus Niveispirillum, 2 strains of Escherichia coli, and 2 strains of Pseudomonas putida, as well as Acinetobacter and Nitrospirillum cells was studied. It is shown that the EO analyzer makes it possible to differentiate situations when bacterial cells interact with a specific bacteriophage from control experiments with no such interaction.The registration of a microbial cell infection with a bacteriophage by the EO analysis method serves as an informative parameter of the presence or absence of cell sensitivity to the bacteriophage studied. The obtained results make it possible to determine the criterion for a specific interaction, which consists of a change in the magnitude of the optical signal by not less than ~10% when a certain amount of bacteriophages is added to the suspension of microbial cells.The results are of interest from a practical point of view since they can be used to create a method for rapid assessment of the effects of bacteriophages on microbial cells.
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publishDate 2020-05-01
publisher LLC "Publishing House OKI"
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series Антибиотики и Химиотерапия
spelling doaj-art-eab6404725d8447a916b961cb3e2d7872025-08-20T02:49:42ZrusLLC "Publishing House OKI"Антибиотики и Химиотерапия0235-29902020-05-01631-2142363Electro-optical Analysis of the Effects of Bacteriophages on Microbial CellsO. I. Guliy0O. A. Karavaeva1O. S. Larionova2S. V. Larionov3L. G. Lovtsova4K. Yu. Uskov5V. D. Bunin6Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences; Saratov State Vavilov Agrarian UniversityInstitute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of SciencesSaratov State Vavilov Agrarian UniversitySaratov State Vavilov Agrarian UniversitySaratov State Vavilov Agrarian UniversitySaratov State Vavilov Agrarian UniversityElosystems GbRThe effect of the ФАb-Sр7 bacteriophage on the change in the electro-optical (EO) parameters of cell suspensions with respect to 14 strains of bacteria of the genus Azospirillum, 2 strains of the genus Niveispirillum, 2 strains of Escherichia coli, and 2 strains of Pseudomonas putida, as well as Acinetobacter and Nitrospirillum cells was studied. It is shown that the EO analyzer makes it possible to differentiate situations when bacterial cells interact with a specific bacteriophage from control experiments with no such interaction.The registration of a microbial cell infection with a bacteriophage by the EO analysis method serves as an informative parameter of the presence or absence of cell sensitivity to the bacteriophage studied. The obtained results make it possible to determine the criterion for a specific interaction, which consists of a change in the magnitude of the optical signal by not less than ~10% when a certain amount of bacteriophages is added to the suspension of microbial cells.The results are of interest from a practical point of view since they can be used to create a method for rapid assessment of the effects of bacteriophages on microbial cells.https://www.antibiotics-chemotherapy.ru/jour/article/view/64bacteriophageselectro-optical analysis of cell suspensions
spellingShingle O. I. Guliy
O. A. Karavaeva
O. S. Larionova
S. V. Larionov
L. G. Lovtsova
K. Yu. Uskov
V. D. Bunin
Electro-optical Analysis of the Effects of Bacteriophages on Microbial Cells
Антибиотики и Химиотерапия
bacteriophages
electro-optical analysis of cell suspensions
title Electro-optical Analysis of the Effects of Bacteriophages on Microbial Cells
title_full Electro-optical Analysis of the Effects of Bacteriophages on Microbial Cells
title_fullStr Electro-optical Analysis of the Effects of Bacteriophages on Microbial Cells
title_full_unstemmed Electro-optical Analysis of the Effects of Bacteriophages on Microbial Cells
title_short Electro-optical Analysis of the Effects of Bacteriophages on Microbial Cells
title_sort electro optical analysis of the effects of bacteriophages on microbial cells
topic bacteriophages
electro-optical analysis of cell suspensions
url https://www.antibiotics-chemotherapy.ru/jour/article/view/64
work_keys_str_mv AT oiguliy electroopticalanalysisoftheeffectsofbacteriophagesonmicrobialcells
AT oakaravaeva electroopticalanalysisoftheeffectsofbacteriophagesonmicrobialcells
AT oslarionova electroopticalanalysisoftheeffectsofbacteriophagesonmicrobialcells
AT svlarionov electroopticalanalysisoftheeffectsofbacteriophagesonmicrobialcells
AT lglovtsova electroopticalanalysisoftheeffectsofbacteriophagesonmicrobialcells
AT kyuuskov electroopticalanalysisoftheeffectsofbacteriophagesonmicrobialcells
AT vdbunin electroopticalanalysisoftheeffectsofbacteriophagesonmicrobialcells