Pisonia Alba Assisted Synthesis of Nanosilver for Wound Healing Activity
Wound infection is a major clinical challenge, impacting patient morbidity and mortality, with significant economic implications. Our research focused on how Pisonia Alba (PA) leaves, which are used to treat wounds, are used to synthesize silver nanoparticles and study their wound healing property....
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Bioinorganic Chemistry and Applications |
| Online Access: | http://dx.doi.org/10.1155/2022/1775198 |
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| author | Suba Kannaiyan D. Easwaramoorthi Karthik Kannan Andal Gopal R. Lakshmipathy Khadijah Mohammedsaleh Katubi Nayef S. Almuaikel Ivan Leandro Rodriguez Rico |
| author_facet | Suba Kannaiyan D. Easwaramoorthi Karthik Kannan Andal Gopal R. Lakshmipathy Khadijah Mohammedsaleh Katubi Nayef S. Almuaikel Ivan Leandro Rodriguez Rico |
| author_sort | Suba Kannaiyan |
| collection | DOAJ |
| description | Wound infection is a major clinical challenge, impacting patient morbidity and mortality, with significant economic implications. Our research focused on how Pisonia Alba (PA) leaves, which are used to treat wounds, are used to synthesize silver nanoparticles and study their wound healing property. UV-visible spectroscopy, X-ray diffraction analysis, and s electron microscope (SEM) analysis were employed to evaluate the synthesized silver nanoparticles. Using DLS and Zeta potential analysis, the size and stability of the Pisonia Alba capped silver nanoparticle were investigated. The results showed that Pisonia Alba extract stabilized silver nanoparticles are 63.88 nm in size and have a spherical shape. Antibacterial and antibiofilm potential of synthesized silver nanoparticles against pathogenic organisms Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) bacteria were investigated. The in vitro cell scratch wounding assay is used to investigate the wound healing properties of synthesized nanoparticles. Pisonia Alba stabilized silver nanoparticles (PA@AgNPs), in comparison to Pisonia Alba (PA) extract, show effective wound healing characteristics by inducing the formation of collagen and serving as a capable wound healing agent. |
| format | Article |
| id | doaj-art-eab484312b084b91afceff831f80f137 |
| institution | Kabale University |
| issn | 1687-479X |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Bioinorganic Chemistry and Applications |
| spelling | doaj-art-eab484312b084b91afceff831f80f1372025-02-03T01:19:58ZengWileyBioinorganic Chemistry and Applications1687-479X2022-01-01202210.1155/2022/1775198Pisonia Alba Assisted Synthesis of Nanosilver for Wound Healing ActivitySuba Kannaiyan0D. Easwaramoorthi1Karthik Kannan2Andal Gopal3R. Lakshmipathy4Khadijah Mohammedsaleh Katubi5Nayef S. Almuaikel6Ivan Leandro Rodriguez Rico7Department of ChemistryDepartment of ChemistrySchool of Advanced Material Sciences and EngineeringDepartment of ChemistryDepartment of ChemistryDepartment of ChemistryChemistry DepartmentFaculty of Chemical and PharmacyWound infection is a major clinical challenge, impacting patient morbidity and mortality, with significant economic implications. Our research focused on how Pisonia Alba (PA) leaves, which are used to treat wounds, are used to synthesize silver nanoparticles and study their wound healing property. UV-visible spectroscopy, X-ray diffraction analysis, and s electron microscope (SEM) analysis were employed to evaluate the synthesized silver nanoparticles. Using DLS and Zeta potential analysis, the size and stability of the Pisonia Alba capped silver nanoparticle were investigated. The results showed that Pisonia Alba extract stabilized silver nanoparticles are 63.88 nm in size and have a spherical shape. Antibacterial and antibiofilm potential of synthesized silver nanoparticles against pathogenic organisms Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) bacteria were investigated. The in vitro cell scratch wounding assay is used to investigate the wound healing properties of synthesized nanoparticles. Pisonia Alba stabilized silver nanoparticles (PA@AgNPs), in comparison to Pisonia Alba (PA) extract, show effective wound healing characteristics by inducing the formation of collagen and serving as a capable wound healing agent.http://dx.doi.org/10.1155/2022/1775198 |
| spellingShingle | Suba Kannaiyan D. Easwaramoorthi Karthik Kannan Andal Gopal R. Lakshmipathy Khadijah Mohammedsaleh Katubi Nayef S. Almuaikel Ivan Leandro Rodriguez Rico Pisonia Alba Assisted Synthesis of Nanosilver for Wound Healing Activity Bioinorganic Chemistry and Applications |
| title | Pisonia Alba Assisted Synthesis of Nanosilver for Wound Healing Activity |
| title_full | Pisonia Alba Assisted Synthesis of Nanosilver for Wound Healing Activity |
| title_fullStr | Pisonia Alba Assisted Synthesis of Nanosilver for Wound Healing Activity |
| title_full_unstemmed | Pisonia Alba Assisted Synthesis of Nanosilver for Wound Healing Activity |
| title_short | Pisonia Alba Assisted Synthesis of Nanosilver for Wound Healing Activity |
| title_sort | pisonia alba assisted synthesis of nanosilver for wound healing activity |
| url | http://dx.doi.org/10.1155/2022/1775198 |
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