Persistent expression of activation markers on Mycobacterium tuberculosis-specific CD4 T cells in smear negative TB patients.

Persistent expression of activation markers on Mycobacterium tuberculosis-specific CD4 T cells in smear negative TB patients.

<h4>Background</h4>T cell activation (HLA-DR, CD-38), proliferation (KI-67), and functional (IFN-γ, TNF-α) markers have recently been shown to be useful in predicting and monitoring anti-TB responses in smear positive TB, but previous research did not characterize the activation and prol...

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Bibliographic Details
Main Authors: Ahmed Esmael, Adane Mihret, Tamrat Abebe, Daniel Mussa, Sebsibe Neway, Joel Ernst, Jyothi Rengarajan, Liya Wassie, Rawleigh Howe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0271234&type=printable
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