Updated MDSGene review on the clinical and genetic spectrum of LRRK2 variants in Parkinson´s disease

Updated MDSGene review on the clinical and genetic spectrum of LRRK2 variants in Parkinson´s disease

Abstract Pathogenic variants in the LRRK2 gene are one of the most commonly identifiable monogenic causes of Parkinson´s disease (PD, PARK-LRRK2). This systematic MDSGene literature review comprehensively summarizes published demographic, clinical, and genetic findings related to LRRK2 variants ( ht...

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Main Authors: Clara Krüger, Shen-Yang Lim, Alissa Buhrmann, Fenja L. Fahrig, Carolin Gabbert, Natascha Bahr, Harutyun Madoev, Connie Marras, Christine Klein, Katja Lohmann
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-025-00881-9
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https://doi.org/10.1038/s41531-025-00881-9

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