Vitamin B12 Deficiency and Hemoglobin H Disease Early Misdiagnosed as Thrombotic Thrombocytopenic Purpura: A Series of Unfortunate Events
We herein would like to report an interesting case of a patient who presented with anemia and thrombocytopenia combined with high serum Lactic Dehydrogenase where Thrombotic Thrombocytopenic Purpura was originally considered. As indicated a central venous catheter was inserted in his subclavian vein...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Hematology |
| Online Access: | http://dx.doi.org/10.1155/2015/478151 |
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| author | Panagiotis Andreadis Stamatia Theodoridou Marily Pasakiotou Stergios Arapoglou Eleni Gigi Evaggelia Vetsiou Efthymia Vlachaki |
| author_facet | Panagiotis Andreadis Stamatia Theodoridou Marily Pasakiotou Stergios Arapoglou Eleni Gigi Evaggelia Vetsiou Efthymia Vlachaki |
| author_sort | Panagiotis Andreadis |
| collection | DOAJ |
| description | We herein would like to report an interesting case of a patient who presented with anemia and thrombocytopenia combined with high serum Lactic Dehydrogenase where Thrombotic Thrombocytopenic Purpura was originally considered. As indicated a central venous catheter was inserted in his subclavian vein which led to mediastinal hematoma and finally intubation and Intensive Care Unit (ICU) hospitalization. After further examination patient was finally diagnosed with B12 deficiency in a setting of H hemoglobinopathy. There have been previous reports where pernicious anemia was originally diagnosed and treated as Thrombotic Thrombocytopenic Purpura but there has been none to our knowledge that was implicated with hemothorax and ICU hospitalization or correlated with thalassemia and we discuss the significance of accurate diagnosis in order to avoid adverse reactions and therapy implications. |
| format | Article |
| id | doaj-art-eaaec3e8e68c4b8ea7751ed8442ca7b9 |
| institution | DOAJ |
| issn | 2090-6560 2090-6579 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Hematology |
| spelling | doaj-art-eaaec3e8e68c4b8ea7751ed8442ca7b92025-08-20T03:20:39ZengWileyCase Reports in Hematology2090-65602090-65792015-01-01201510.1155/2015/478151478151Vitamin B12 Deficiency and Hemoglobin H Disease Early Misdiagnosed as Thrombotic Thrombocytopenic Purpura: A Series of Unfortunate EventsPanagiotis Andreadis0Stamatia Theodoridou1Marily Pasakiotou2Stergios Arapoglou3Eleni Gigi4Evaggelia Vetsiou5Efthymia Vlachaki6Second Department of Internal Medicine, Aristotle University, Hippokration Hospital, 54642 Thessaloniki, GreeceThalassemia Unit, Hippokration Hospital, 54642 Thessaloniki, GreeceIntensive Care Unit, Hippokration Hospital, 54642 Thessaloniki, GreeceFifth Surgical Clinic, Aristotle University, Hippokration Hospital, 54642 Thessaloniki, GreeceSecond Department of Internal Medicine, Aristotle University, Hippokration Hospital, 54642 Thessaloniki, GreeceSecond Department of Internal Medicine, Aristotle University, Hippokration Hospital, 54642 Thessaloniki, GreeceSecond Department of Internal Medicine, Aristotle University, Hippokration Hospital, 54642 Thessaloniki, GreeceWe herein would like to report an interesting case of a patient who presented with anemia and thrombocytopenia combined with high serum Lactic Dehydrogenase where Thrombotic Thrombocytopenic Purpura was originally considered. As indicated a central venous catheter was inserted in his subclavian vein which led to mediastinal hematoma and finally intubation and Intensive Care Unit (ICU) hospitalization. After further examination patient was finally diagnosed with B12 deficiency in a setting of H hemoglobinopathy. There have been previous reports where pernicious anemia was originally diagnosed and treated as Thrombotic Thrombocytopenic Purpura but there has been none to our knowledge that was implicated with hemothorax and ICU hospitalization or correlated with thalassemia and we discuss the significance of accurate diagnosis in order to avoid adverse reactions and therapy implications.http://dx.doi.org/10.1155/2015/478151 |
| spellingShingle | Panagiotis Andreadis Stamatia Theodoridou Marily Pasakiotou Stergios Arapoglou Eleni Gigi Evaggelia Vetsiou Efthymia Vlachaki Vitamin B12 Deficiency and Hemoglobin H Disease Early Misdiagnosed as Thrombotic Thrombocytopenic Purpura: A Series of Unfortunate Events Case Reports in Hematology |
| title | Vitamin B12 Deficiency and Hemoglobin H Disease Early Misdiagnosed as Thrombotic Thrombocytopenic Purpura: A Series of Unfortunate Events |
| title_full | Vitamin B12 Deficiency and Hemoglobin H Disease Early Misdiagnosed as Thrombotic Thrombocytopenic Purpura: A Series of Unfortunate Events |
| title_fullStr | Vitamin B12 Deficiency and Hemoglobin H Disease Early Misdiagnosed as Thrombotic Thrombocytopenic Purpura: A Series of Unfortunate Events |
| title_full_unstemmed | Vitamin B12 Deficiency and Hemoglobin H Disease Early Misdiagnosed as Thrombotic Thrombocytopenic Purpura: A Series of Unfortunate Events |
| title_short | Vitamin B12 Deficiency and Hemoglobin H Disease Early Misdiagnosed as Thrombotic Thrombocytopenic Purpura: A Series of Unfortunate Events |
| title_sort | vitamin b12 deficiency and hemoglobin h disease early misdiagnosed as thrombotic thrombocytopenic purpura a series of unfortunate events |
| url | http://dx.doi.org/10.1155/2015/478151 |
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