New Horizon in Selective Tocols Extraction from Deodorizer Distillates Under Mild Conditions by Using Deep Eutectic Solvents
Tocols are commonly known as vitamin E, which comprise tocopherols and tocotrienols. Although vegetable oils are natural sources of tocols, deodorizer distillates (DDs) are attractive feedstock due to their potential abundance from oil refining processes and economic price. Deep eutectic solvents (D...
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2025-03-01
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| author | Dian Maria Ulfa Asep Bayu Siti Irma Rahmawati Peni Ahmadi Masteria Yunovilsa Putra Surachai Karnjanakom Guoqing Guan Abdul Mun’im |
| author_facet | Dian Maria Ulfa Asep Bayu Siti Irma Rahmawati Peni Ahmadi Masteria Yunovilsa Putra Surachai Karnjanakom Guoqing Guan Abdul Mun’im |
| author_sort | Dian Maria Ulfa |
| collection | DOAJ |
| description | Tocols are commonly known as vitamin E, which comprise tocopherols and tocotrienols. Although vegetable oils are natural sources of tocols, deodorizer distillates (DDs) are attractive feedstock due to their potential abundance from oil refining processes and economic price. Deep eutectic solvents (DESs) are a family of neoteric solvents that show promising performance for tocols extraction. Besides their characters occupying the green chemistry concept, this review presents the current research on the potential performances of DESs in extracting tocols selectively and efficiently from DDs. The application of DESs in tocols extraction is presented considering three different ways: mono-phasic, in situ DESs formation, and bi-phasic systems. The basic principles of intermolecular interactions (H-bond, van der Walls bond, and misfit interaction) between DESs or their components with tocols are discussed to understand the mechanism by which DESs selectively extract tocols from the mixture. This is mainly observed to be a function of the intrinsic properties of DESs and/or tocols, which could be beneficial for tuning the appropriate DESs for extracting tocols selectively and effectively under mild operation conditions. This review is expected to provide insight in the potential application of DESs in the extracting of natural compounds with a phenolic structure and also briefly discusses the toxicity of DESs. |
| format | Article |
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| institution | DOAJ |
| issn | 1420-3049 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | MDPI AG |
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| series | Molecules |
| spelling | doaj-art-ea9bc2cbcc614c78a5a1d05732273d9c2025-08-20T02:42:22ZengMDPI AGMolecules1420-30492025-03-01306121710.3390/molecules30061217New Horizon in Selective Tocols Extraction from Deodorizer Distillates Under Mild Conditions by Using Deep Eutectic SolventsDian Maria Ulfa0Asep Bayu1Siti Irma Rahmawati2Peni Ahmadi3Masteria Yunovilsa Putra4Surachai Karnjanakom5Guoqing Guan6Abdul Mun’im7Faculty of Pharmacy, Cluster of Health Sciences Building, Universitas Indonesia, Depok 16424, West Java, IndonesiaNational Metabolomics Collaborative Research Center, Faculty of Pharmacy, Cluster of Health Sciences Building, Universitas Indonesia, Depok 16424, West Java, IndonesiaNational Metabolomics Collaborative Research Center, Faculty of Pharmacy, Cluster of Health Sciences Building, Universitas Indonesia, Depok 16424, West Java, IndonesiaNational Metabolomics Collaborative Research Center, Faculty of Pharmacy, Cluster of Health Sciences Building, Universitas Indonesia, Depok 16424, West Java, IndonesiaNational Metabolomics Collaborative Research Center, Faculty of Pharmacy, Cluster of Health Sciences Building, Universitas Indonesia, Depok 16424, West Java, IndonesiaDepartment of Chemistry, Faculty of Science, Rangsit University, Pathumthani 12000, ThailandEnergy Conversion Engineering Laboratory, Institute of Regional Innovation, Hirosaki University, 3-Bunkyocho, Hirosaki 036-8561, JapanFaculty of Pharmacy, Cluster of Health Sciences Building, Universitas Indonesia, Depok 16424, West Java, IndonesiaTocols are commonly known as vitamin E, which comprise tocopherols and tocotrienols. Although vegetable oils are natural sources of tocols, deodorizer distillates (DDs) are attractive feedstock due to their potential abundance from oil refining processes and economic price. Deep eutectic solvents (DESs) are a family of neoteric solvents that show promising performance for tocols extraction. Besides their characters occupying the green chemistry concept, this review presents the current research on the potential performances of DESs in extracting tocols selectively and efficiently from DDs. The application of DESs in tocols extraction is presented considering three different ways: mono-phasic, in situ DESs formation, and bi-phasic systems. The basic principles of intermolecular interactions (H-bond, van der Walls bond, and misfit interaction) between DESs or their components with tocols are discussed to understand the mechanism by which DESs selectively extract tocols from the mixture. This is mainly observed to be a function of the intrinsic properties of DESs and/or tocols, which could be beneficial for tuning the appropriate DESs for extracting tocols selectively and effectively under mild operation conditions. This review is expected to provide insight in the potential application of DESs in the extracting of natural compounds with a phenolic structure and also briefly discusses the toxicity of DESs.https://www.mdpi.com/1420-3049/30/6/1217tocotrienoltocopherolextractiondeodorizer distillatesdeep eutectic solvents |
| spellingShingle | Dian Maria Ulfa Asep Bayu Siti Irma Rahmawati Peni Ahmadi Masteria Yunovilsa Putra Surachai Karnjanakom Guoqing Guan Abdul Mun’im New Horizon in Selective Tocols Extraction from Deodorizer Distillates Under Mild Conditions by Using Deep Eutectic Solvents Molecules tocotrienol tocopherol extraction deodorizer distillates deep eutectic solvents |
| title | New Horizon in Selective Tocols Extraction from Deodorizer Distillates Under Mild Conditions by Using Deep Eutectic Solvents |
| title_full | New Horizon in Selective Tocols Extraction from Deodorizer Distillates Under Mild Conditions by Using Deep Eutectic Solvents |
| title_fullStr | New Horizon in Selective Tocols Extraction from Deodorizer Distillates Under Mild Conditions by Using Deep Eutectic Solvents |
| title_full_unstemmed | New Horizon in Selective Tocols Extraction from Deodorizer Distillates Under Mild Conditions by Using Deep Eutectic Solvents |
| title_short | New Horizon in Selective Tocols Extraction from Deodorizer Distillates Under Mild Conditions by Using Deep Eutectic Solvents |
| title_sort | new horizon in selective tocols extraction from deodorizer distillates under mild conditions by using deep eutectic solvents |
| topic | tocotrienol tocopherol extraction deodorizer distillates deep eutectic solvents |
| url | https://www.mdpi.com/1420-3049/30/6/1217 |
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