Discovery of Arylfuran and Carbohydrate Derivatives from the BraCoLi Library as Potential Zika Virus NS3<sup>pro</sup> Inhibitors

Discovery of Arylfuran and Carbohydrate Derivatives from the BraCoLi Library as Potential Zika Virus NS3<sup>pro</sup> Inhibitors

<b>Background/Objectives:</b> Zika fever is a disease caused by the Zika virus (ZIKV). Symptomatic cases may be associated with neurological disorders in adults, as well as congenital Zika syndrome and other birth defects during pregnancy. In 2016, Zika fever was considered a public heal...

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Main Authors: Fernanda Kelly Marcelino e Oliveira, Beatriz Murta Rezende Moraes Ribeiro, Ellen Gonçalves de Oliveira, Marina Mol Sena Andrade Verzola, Thales Kronenberger, Vinícius Gonçalves Maltarollo, Ricardo José Alves, Renata Barbosa de Oliveira, Rafaela Salgado Ferreira, Jônatas Santos Abrahão, Mateus Sá Magalhães Serafim
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Future Pharmacology
Subjects:
antiviral activity
arylfuran derivative
consensus docking
MTT
NS3<sup>pro</sup>
Zika virus
Online Access:https://www.mdpi.com/2673-9879/5/1/9
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