Postoperative adjuvant chemotherapy in patients with stage II early onset colorectal cancer: exploration and discovery using real-world data and the SEER database
Background and aimThe incidence of early-onset colorectal cancer (EOCRC) is rising, yet intensive postoperative adjuvant chemotherapy (ACT) often results in overtreatment with minimal prognostic benefit. This study aims to assess the therapeutic necessity of ACT in stage II EOCRC patients and to ide...
Saved in:
| Main Authors: | Shikun Cao, Yihuan Qiao, Lijun Wu, Qi Chen, Kai Tian, Jipeng Li, Chungen Xing |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-05-01
|
| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2025.1566569/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Early-onset colorectal cancer: a retrospective study of demographic, clinicopathological, and molecular characteristics in a single Chinese center
by: Zongyao Chen, et al.
Published: (2025-08-01) -
The efficiency of neoadjuvant chemotherapy in colon cancer with mismatch repair deficiency
by: Wu Yunlong, et al.
Published: (2023-02-01) -
Clinical Molecular Immunohistochemistry Mismatch Repair Mutations in Lynch Syndrome in Patients Under 50 Years: A Systematic Review
by: Bogdan Adrian Manta, et al.
Published: (2025-04-01) -
This is not Lynch syndrome: lessons from misattributed diagnoses in constitutional mismatch repair deficiency
by: A.H. Mohammad, et al.
Published: (2024-12-01) -
Efficacy and safety of neoadjuvant toripalimab plus chemotherapy in localized deficient mismatch repair/microsatellite instability-high gastric or esophagogastric junction adenocarcinoma (NICE): a multicentre, single-arm, exploratory phase 2 studyResearch in context
by: Liying Zhao, et al.
Published: (2025-09-01)