Autophagosome Proteins LC3A, LC3B and LC3C Have Distinct Subcellular Distribution Kinetics and Expression in Cancer Cell Lines.
LC3s (MAP1-LC3A, B and C) are structural proteins of autophagosomal membranes, widely used as biomarkers of autophagy. Whether these three LC3 proteins have a similar biological role in autophagy remains obscure. We examine in parallel the subcellular expression patterns of the three LC3 proteins in...
Saved in:
| Main Authors: | Michael I Koukourakis, Dimitra Kalamida, Alexandra Giatromanolaki, Christos E Zois, Efthimios Sivridis, Stamatia Pouliliou, Achilleas Mitrakas, Kevin C Gatter, Adrian L Harris |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2015-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0137675&type=printable |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
HRES-1/Rab4 promotes the formation of LC3(+) autophagosomes and the accumulation of mitochondria during autophagy.
by: Gergely Talaber, et al.
Published: (2014-01-01) -
Critical assessment of LC3/GABARAP ligands used for degrader development and ligandability of LC3/GABARAP binding pockets
by: Martin P. Schwalm, et al.
Published: (2024-11-01) -
Autophagy and LC3-associated phagocytosis: similarities and differences
by: B. R. Ibragimov, et al.
Published: (2023-04-01) -
A non‐fluorescent immunohistochemistry method for measuring autophagy flux using MAP1LC3/LC3 and SQSTM1 as core markers
by: Shahla Shojaei, et al.
Published: (2025-06-01) -
Normal tissue radioprotection by amifostine via Warburg-type effects
by: Michael I. Koukourakis, et al.
Published: (2016-08-01)