Astragaloside IV attenuates podocyte apoptosis via regulating TXNIP/NLRP3/GSDMD signaling pathway in diabetic nephropathy

Astragaloside IV attenuates podocyte apoptosis via regulating TXNIP/NLRP3/GSDMD signaling pathway in diabetic nephropathy

Abstract Objectives Among all the diabetes complications brought on by persistent inflammation is diabetic kidney disease (DKD). One essential method of the inflammatory response's programmed cell death is anthrax. One of the main causes of diabetic renal disease progression in a high-glycemic...

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Bibliographic Details
Main Authors: Zhibo Hu, Yu Zhou, Cailing Gao, Junfen Liu, Congqing Pan, Jun Guo
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Diabetology & Metabolic Syndrome
Subjects:
Astragaloside IV
Diabetic kidney disease
Pyroptosis
TXNIP
NLRP3 inflammasome
Online Access:https://doi.org/10.1186/s13098-024-01546-y
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