Semaglutide and adenosine alleviate obesity-induced kidney injury, with observed modulation of the Txnip/NLRP3 pathway

Semaglutide and adenosine alleviate obesity-induced kidney injury, with observed modulation of the Txnip/NLRP3 pathway

Abstract Objective This study was designed to evaluate the effects of Semaglutide and adenosine on kidney protein expression in obese mice induced by a high-fat diet (HFD), to identify signaling pathways involved in the obesity-related glomerulonephropathy (ORG) regulation using a proteomics approac...

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Bibliographic Details
Main Authors: Shuqi Wang, Xiaoyu Pan, Ruiqing Liang, Shuchun Chen
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Diabetology & Metabolic Syndrome
Subjects:
Obesity
Semaglutide
Adenosine
Obesity-related glomerulonephropathy
Proteomics
Online Access:https://doi.org/10.1186/s13098-025-01736-2
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