Optimal control of a mathematical model for cancer chemotherapy under tumor heterogeneity
We consider cancer chemotherapy as an optimal control problem with the aim to minimize a combination of the tumor volume and side effects over an a priori specified therapy horizon when the tumor consists of a heterogeneous agglomeration of many subpopulations. The mathematical model, which accounts...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
AIMS Press
2016-07-01
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| Series: | Mathematical Biosciences and Engineering |
| Subjects: | |
| Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2016040 |
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