Photodynamic Therapy of Presumed Choroidal Metastasis Secondary to Colorectal Carcinoma: Literature Review

Colorectal cancer may yield metastasis to the choroid. Its management may be challenging, since there is no consensus about treatment. We describe a case of a 70-year-old male with colon cancer who complained of worsening visual acuity of his better-seeing eye to 20/40 secondary to a nonpigmented ch...

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Main Authors: Laurentino Biccas Neto, José Z. Pulido, Gustavo B. Melo, Luiz H. Lima, Eduardo B. Rodrigues
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Ophthalmological Medicine
Online Access:http://dx.doi.org/10.1155/2020/6490535
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author Laurentino Biccas Neto
José Z. Pulido
Gustavo B. Melo
Luiz H. Lima
Eduardo B. Rodrigues
author_facet Laurentino Biccas Neto
José Z. Pulido
Gustavo B. Melo
Luiz H. Lima
Eduardo B. Rodrigues
author_sort Laurentino Biccas Neto
collection DOAJ
description Colorectal cancer may yield metastasis to the choroid. Its management may be challenging, since there is no consensus about treatment. We describe a case of a 70-year-old male with colon cancer who complained of worsening visual acuity of his better-seeing eye to 20/40 secondary to a nonpigmented choroidal mass of medium reflectivity under the inferior temporal arcade and neurosensory foveal detachment. Besides systemic chemotherapy, local treatment with verteporfin photodynamic therapy (vPDT) was performed. After one month, visual acuity improved to 20/25 and subretinal fluid faded. In conclusion, vPDT may be a useful adjuvant treatment modality for choroidal metastasis secondary to colorectal cancer.
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institution Kabale University
issn 2090-6722
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publishDate 2020-01-01
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series Case Reports in Ophthalmological Medicine
spelling doaj-art-ea82f9ebe2da4fc4b370396f590ab1d92025-02-03T01:27:04ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302020-01-01202010.1155/2020/64905356490535Photodynamic Therapy of Presumed Choroidal Metastasis Secondary to Colorectal Carcinoma: Literature ReviewLaurentino Biccas Neto0José Z. Pulido1Gustavo B. Melo2Luiz H. Lima3Eduardo B. Rodrigues4Ocular Oftalmologia, Vitória, BrazilDepartment of Oncology, Hospital Evangélico, Cachoeiro do Itapemirim, BrazilHospital de Olhos de Sergipe, Aracaju, BrazilDepartment of Ophthalmology, Universidade Federal de São Paulo, São Paulo, BrazilDepartment of Ophthalmology, Universidade Federal de São Paulo, São Paulo, BrazilColorectal cancer may yield metastasis to the choroid. Its management may be challenging, since there is no consensus about treatment. We describe a case of a 70-year-old male with colon cancer who complained of worsening visual acuity of his better-seeing eye to 20/40 secondary to a nonpigmented choroidal mass of medium reflectivity under the inferior temporal arcade and neurosensory foveal detachment. Besides systemic chemotherapy, local treatment with verteporfin photodynamic therapy (vPDT) was performed. After one month, visual acuity improved to 20/25 and subretinal fluid faded. In conclusion, vPDT may be a useful adjuvant treatment modality for choroidal metastasis secondary to colorectal cancer.http://dx.doi.org/10.1155/2020/6490535
spellingShingle Laurentino Biccas Neto
José Z. Pulido
Gustavo B. Melo
Luiz H. Lima
Eduardo B. Rodrigues
Photodynamic Therapy of Presumed Choroidal Metastasis Secondary to Colorectal Carcinoma: Literature Review
Case Reports in Ophthalmological Medicine
title Photodynamic Therapy of Presumed Choroidal Metastasis Secondary to Colorectal Carcinoma: Literature Review
title_full Photodynamic Therapy of Presumed Choroidal Metastasis Secondary to Colorectal Carcinoma: Literature Review
title_fullStr Photodynamic Therapy of Presumed Choroidal Metastasis Secondary to Colorectal Carcinoma: Literature Review
title_full_unstemmed Photodynamic Therapy of Presumed Choroidal Metastasis Secondary to Colorectal Carcinoma: Literature Review
title_short Photodynamic Therapy of Presumed Choroidal Metastasis Secondary to Colorectal Carcinoma: Literature Review
title_sort photodynamic therapy of presumed choroidal metastasis secondary to colorectal carcinoma literature review
url http://dx.doi.org/10.1155/2020/6490535
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