miR-155 targets SOCS1 to modulate the phenotype transition of M1 macrophage in distraction osteogenesis promoted by PTH administration

Abstract Background Distraction osteogenesis (DO) is a highly effective method for bone regeneration. However, its prolonged treatment duration limits its clinical application. Parathyroid hormone (PTH) can promote distraction osteogenesis, but the underlying mechanism remains unclear. During distra...

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Bibliographic Details
Main Authors: Yongdi Li, Liyue Tian, Zhishan Yang, Yiheng Liu, Duchenhui Li, Zhenglong Tang
Format: Article
Language:English
Published: BMC 2025-05-01
Series:European Journal of Medical Research
Subjects:
Online Access:https://doi.org/10.1186/s40001-025-02683-4
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