Antigenic properties estimation for legumain protein recombinant analogue of trematoda Opisthorchis felineus, causing human opisthorchiasis
We estimated potential of protein legumain from opisthorchiasis agent O. felineus for application in immunodiagnosis of this disease. Bacterially expressed recombinant protein (rOF49-leg) showed strong difference in Enzyme-linked immunosorbent assay (ELISA) between infected and negative sera. These...
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| Format: | Article |
| Language: | English |
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Siberian State Medical University (Tomsk)
2012-12-01
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| Series: | Бюллетень сибирской медицины |
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| Online Access: | https://bulletin.ssmu.ru/jour/article/view/897 |
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| author | I. A. Razumov M. N. Lvova Ye. P. Ponomareva A. V. Katokhin V. A. Petrenko A. E. Sazonov L. M. Ogorodova V. V. Novitsky A. Yu. Sivkov V. A. Mordvinov |
| author_facet | I. A. Razumov M. N. Lvova Ye. P. Ponomareva A. V. Katokhin V. A. Petrenko A. E. Sazonov L. M. Ogorodova V. V. Novitsky A. Yu. Sivkov V. A. Mordvinov |
| author_sort | I. A. Razumov |
| collection | DOAJ |
| description | We estimated potential of protein legumain from opisthorchiasis agent O. felineus for application in immunodiagnosis of this disease. Bacterially expressed recombinant protein (rOF49-leg) showed strong difference in Enzyme-linked immunosorbent assay (ELISA) between infected and negative sera. These results suggest the potential of this antigen for development of serodiagnostic test for human opisthorchiasis. |
| format | Article |
| id | doaj-art-ea6f6de95ea04364bcc1a388fb26fc79 |
| institution | Kabale University |
| issn | 1682-0363 1819-3684 |
| language | English |
| publishDate | 2012-12-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj-art-ea6f6de95ea04364bcc1a388fb26fc792025-08-20T04:00:19ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842012-12-0111616617110.20538/1682-0363-2012-6-166-171686Antigenic properties estimation for legumain protein recombinant analogue of trematoda Opisthorchis felineus, causing human opisthorchiasisI. A. Razumov0M. N. Lvova1Ye. P. Ponomareva2A. V. Katokhin3V. A. Petrenko4A. E. Sazonov5L. M. Ogorodova6V. V. Novitsky7A. Yu. Sivkov8V. A. Mordvinov9Институт цитологии и генетики СО РАН, г. НовосибирскИнститут цитологии и генетики СО РАН, г. НовосибирскИнститут цитологии и генетики СО РАН, г. НовосибирскИнститут цитологии и генетики СО РАН, г. НовосибирскИнститут цитологии и генетики СО РАН, г. НовосибирскИнститут цитологии и генетики СО РАН, г. НовосибирскСибирский государственный медицинский университет, г. ТомскСибирский государственный медицинский университет, г. ТомскИнститут цитологии и генетики СО РАН, г. НовосибирскИнститут цитологии и генетики СО РАН, г. НовосибирскWe estimated potential of protein legumain from opisthorchiasis agent O. felineus for application in immunodiagnosis of this disease. Bacterially expressed recombinant protein (rOF49-leg) showed strong difference in Enzyme-linked immunosorbent assay (ELISA) between infected and negative sera. These results suggest the potential of this antigen for development of serodiagnostic test for human opisthorchiasis.https://bulletin.ssmu.ru/jour/article/view/897opisthorchis felineusopisthorchiasisrecombinant proteinslegumainimmunodiagnosis |
| spellingShingle | I. A. Razumov M. N. Lvova Ye. P. Ponomareva A. V. Katokhin V. A. Petrenko A. E. Sazonov L. M. Ogorodova V. V. Novitsky A. Yu. Sivkov V. A. Mordvinov Antigenic properties estimation for legumain protein recombinant analogue of trematoda Opisthorchis felineus, causing human opisthorchiasis Бюллетень сибирской медицины opisthorchis felineus opisthorchiasis recombinant proteins legumain immunodiagnosis |
| title | Antigenic properties estimation for legumain protein recombinant analogue of trematoda Opisthorchis felineus, causing human opisthorchiasis |
| title_full | Antigenic properties estimation for legumain protein recombinant analogue of trematoda Opisthorchis felineus, causing human opisthorchiasis |
| title_fullStr | Antigenic properties estimation for legumain protein recombinant analogue of trematoda Opisthorchis felineus, causing human opisthorchiasis |
| title_full_unstemmed | Antigenic properties estimation for legumain protein recombinant analogue of trematoda Opisthorchis felineus, causing human opisthorchiasis |
| title_short | Antigenic properties estimation for legumain protein recombinant analogue of trematoda Opisthorchis felineus, causing human opisthorchiasis |
| title_sort | antigenic properties estimation for legumain protein recombinant analogue of trematoda opisthorchis felineus causing human opisthorchiasis |
| topic | opisthorchis felineus opisthorchiasis recombinant proteins legumain immunodiagnosis |
| url | https://bulletin.ssmu.ru/jour/article/view/897 |
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