Active Holistic Surveillance: The Nutritional Aspect of Delayed Intervention in Prostate Cancer
Purpose. Active surveillance is an emergent strategy for management of indolent prostate cancer. Our institution’s watchful waiting protocol, Active Holistic Surveillance (AHS), implements close monitoring for disease progression along with various chemopreventive agents and attempts to reduce unnec...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Journal of Nutrition and Metabolism |
| Online Access: | http://dx.doi.org/10.1155/2016/2917065 |
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| author | Courtney J. Berg David J. Habibian Aaron E. Katz Kaitlin E. Kosinski Anthony T. Corcoran Andrew S. Fontes |
| author_facet | Courtney J. Berg David J. Habibian Aaron E. Katz Kaitlin E. Kosinski Anthony T. Corcoran Andrew S. Fontes |
| author_sort | Courtney J. Berg |
| collection | DOAJ |
| description | Purpose. Active surveillance is an emergent strategy for management of indolent prostate cancer. Our institution’s watchful waiting protocol, Active Holistic Surveillance (AHS), implements close monitoring for disease progression along with various chemopreventive agents and attempts to reduce unnecessary biopsies. Our objective is to report on the treatment rates of men on our AHS protocol as well as determine reasons for progression. Materials/Methods. Low risk and low-intermediate risk patients were enrolled in AHS at Winthrop University Hospital between February 2002 and August 2015. Our IRB-approved study analyzed survival rate, discontinuation rates, and definitive treatments for patients in our AHS cohort. Results. 235 patients met inclusion criteria. Median age and follow-up for the cohort were 66 (44–88) years and 42 (3–166) months, respectively. The overall survival for the cohort was 99.6% and the disease specific survival was 100%. A total of 27 (11.5%) patients discontinued AHS. Conclusion. The incorporation of chemopreventive agents in our AHS protocol has allowed patients to prolong definitive treatment for many years. Longer follow-up and additional studies are necessary to further validate the effectiveness of AHS. |
| format | Article |
| id | doaj-art-ea6ee6882ba846a8935cefb41c2e75cf |
| institution | OA Journals |
| issn | 2090-0724 2090-0732 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Nutrition and Metabolism |
| spelling | doaj-art-ea6ee6882ba846a8935cefb41c2e75cf2025-08-20T02:21:54ZengWileyJournal of Nutrition and Metabolism2090-07242090-07322016-01-01201610.1155/2016/29170652917065Active Holistic Surveillance: The Nutritional Aspect of Delayed Intervention in Prostate CancerCourtney J. Berg0David J. Habibian1Aaron E. Katz2Kaitlin E. Kosinski3Anthony T. Corcoran4Andrew S. Fontes5Department of Urology, Winthrop University Hospital, Mineola, NY 11501, USADepartment of Urology, Winthrop University Hospital, Mineola, NY 11501, USADepartment of Urology, Winthrop University Hospital, Mineola, NY 11501, USADepartment of Urology, Winthrop University Hospital, Mineola, NY 11501, USADepartment of Urology, Winthrop University Hospital, Mineola, NY 11501, USADepartment of Urology, Winthrop University Hospital, Mineola, NY 11501, USAPurpose. Active surveillance is an emergent strategy for management of indolent prostate cancer. Our institution’s watchful waiting protocol, Active Holistic Surveillance (AHS), implements close monitoring for disease progression along with various chemopreventive agents and attempts to reduce unnecessary biopsies. Our objective is to report on the treatment rates of men on our AHS protocol as well as determine reasons for progression. Materials/Methods. Low risk and low-intermediate risk patients were enrolled in AHS at Winthrop University Hospital between February 2002 and August 2015. Our IRB-approved study analyzed survival rate, discontinuation rates, and definitive treatments for patients in our AHS cohort. Results. 235 patients met inclusion criteria. Median age and follow-up for the cohort were 66 (44–88) years and 42 (3–166) months, respectively. The overall survival for the cohort was 99.6% and the disease specific survival was 100%. A total of 27 (11.5%) patients discontinued AHS. Conclusion. The incorporation of chemopreventive agents in our AHS protocol has allowed patients to prolong definitive treatment for many years. Longer follow-up and additional studies are necessary to further validate the effectiveness of AHS.http://dx.doi.org/10.1155/2016/2917065 |
| spellingShingle | Courtney J. Berg David J. Habibian Aaron E. Katz Kaitlin E. Kosinski Anthony T. Corcoran Andrew S. Fontes Active Holistic Surveillance: The Nutritional Aspect of Delayed Intervention in Prostate Cancer Journal of Nutrition and Metabolism |
| title | Active Holistic Surveillance: The Nutritional Aspect of Delayed Intervention in Prostate Cancer |
| title_full | Active Holistic Surveillance: The Nutritional Aspect of Delayed Intervention in Prostate Cancer |
| title_fullStr | Active Holistic Surveillance: The Nutritional Aspect of Delayed Intervention in Prostate Cancer |
| title_full_unstemmed | Active Holistic Surveillance: The Nutritional Aspect of Delayed Intervention in Prostate Cancer |
| title_short | Active Holistic Surveillance: The Nutritional Aspect of Delayed Intervention in Prostate Cancer |
| title_sort | active holistic surveillance the nutritional aspect of delayed intervention in prostate cancer |
| url | http://dx.doi.org/10.1155/2016/2917065 |
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