A comprehensive dataset of therapeutic peptides on multi-function property and structure information
Abstract This paper presents a comprehensive dataset comprising 58,583 experimentally validated therapeutic peptides with annotated structure information. These peptides are grouped into 47 categories based on their function or therapeutic property like antimicrobial or glucose-regulatory, of which...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2025-07-01
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| Series: | Scientific Data |
| Online Access: | https://doi.org/10.1038/s41597-025-05528-1 |
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| _version_ | 1849238185612148736 |
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| author | Baichuan Xiao Yixiang Zhou Long Zhao Haodong Huang Xuwen Fei Yong-Biao Zhang |
| author_facet | Baichuan Xiao Yixiang Zhou Long Zhao Haodong Huang Xuwen Fei Yong-Biao Zhang |
| author_sort | Baichuan Xiao |
| collection | DOAJ |
| description | Abstract This paper presents a comprehensive dataset comprising 58,583 experimentally validated therapeutic peptides with annotated structure information. These peptides are grouped into 47 categories based on their function or therapeutic property like antimicrobial or glucose-regulatory, of which 21,130 are multi-function peptides and 54,722 possess structural annotation information. We believe this dataset can be useful for the relevant research of therapeutic peptides, especially for computational tool developments in therapeutic peptide discovery and further exploration of the ‘sequence-structure-function’ relationship for therapeutic peptides. |
| format | Article |
| id | doaj-art-ea6c52c729d4466982094f8bea6e3920 |
| institution | Kabale University |
| issn | 2052-4463 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Data |
| spelling | doaj-art-ea6c52c729d4466982094f8bea6e39202025-08-20T04:01:43ZengNature PortfolioScientific Data2052-44632025-07-011211710.1038/s41597-025-05528-1A comprehensive dataset of therapeutic peptides on multi-function property and structure informationBaichuan Xiao0Yixiang Zhou1Long Zhao2Haodong Huang3Xuwen Fei4Yong-Biao Zhang5School of Engineering Medicine, Beihang UniversitySchool of Engineering Medicine, Beihang UniversitySchool of Materials and Chemical Engineering, Beijing Institute of Petrochemical TechnologySchool of Engineering Medicine, Beihang UniversitySchool of Mathematics and Statistics, Wuhan UniversitySchool of Engineering Medicine, Beihang UniversityAbstract This paper presents a comprehensive dataset comprising 58,583 experimentally validated therapeutic peptides with annotated structure information. These peptides are grouped into 47 categories based on their function or therapeutic property like antimicrobial or glucose-regulatory, of which 21,130 are multi-function peptides and 54,722 possess structural annotation information. We believe this dataset can be useful for the relevant research of therapeutic peptides, especially for computational tool developments in therapeutic peptide discovery and further exploration of the ‘sequence-structure-function’ relationship for therapeutic peptides.https://doi.org/10.1038/s41597-025-05528-1 |
| spellingShingle | Baichuan Xiao Yixiang Zhou Long Zhao Haodong Huang Xuwen Fei Yong-Biao Zhang A comprehensive dataset of therapeutic peptides on multi-function property and structure information Scientific Data |
| title | A comprehensive dataset of therapeutic peptides on multi-function property and structure information |
| title_full | A comprehensive dataset of therapeutic peptides on multi-function property and structure information |
| title_fullStr | A comprehensive dataset of therapeutic peptides on multi-function property and structure information |
| title_full_unstemmed | A comprehensive dataset of therapeutic peptides on multi-function property and structure information |
| title_short | A comprehensive dataset of therapeutic peptides on multi-function property and structure information |
| title_sort | comprehensive dataset of therapeutic peptides on multi function property and structure information |
| url | https://doi.org/10.1038/s41597-025-05528-1 |
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