Application of the Principles of Green Chemistry for the Development of a New and Sensitive Method for Analysis of Ertapenem Sodium by Capillary Electrophoresis

An innovative method is validated for the analysis of ertapenem sodium by capillary electrophoresis using potassium phosphate buffer 10 mM pH 7 and 15 kV voltage, in the concentration range of 70 to 120 μg mL−1. Ertapenem had a migration time of 3.15 minutes and the linearity curve was y = 2281.7 x...

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Main Authors: Tahisa Marcela Pedroso, Ann Van Schepdael, Hérida Regina Nunes Salgado
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:International Journal of Analytical Chemistry
Online Access:http://dx.doi.org/10.1155/2019/1456313
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author Tahisa Marcela Pedroso
Ann Van Schepdael
Hérida Regina Nunes Salgado
author_facet Tahisa Marcela Pedroso
Ann Van Schepdael
Hérida Regina Nunes Salgado
author_sort Tahisa Marcela Pedroso
collection DOAJ
description An innovative method is validated for the analysis of ertapenem sodium by capillary electrophoresis using potassium phosphate buffer 10 mM pH 7 and 15 kV voltage, in the concentration range of 70 to 120 μg mL−1. Ertapenem had a migration time of 3.15 minutes and the linearity curve was y = 2281.7 x - 24495 with a R2 = 0.9994. Thus, we propose a routine analysis method that meets the principles of green analytical chemistry for the routine analysis of ertapenem sodium by capillary electrophoresis.
format Article
id doaj-art-ea6854285a4c4269ba40822c18da3eba
institution OA Journals
issn 1687-8760
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publishDate 2019-01-01
publisher Wiley
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series International Journal of Analytical Chemistry
spelling doaj-art-ea6854285a4c4269ba40822c18da3eba2025-08-20T02:21:54ZengWileyInternational Journal of Analytical Chemistry1687-87601687-87792019-01-01201910.1155/2019/14563131456313Application of the Principles of Green Chemistry for the Development of a New and Sensitive Method for Analysis of Ertapenem Sodium by Capillary ElectrophoresisTahisa Marcela Pedroso0Ann Van Schepdael1Hérida Regina Nunes Salgado2UNESP-Univ Estadual Paulista, Faculdade de Ciências Farmacêuticas, Araraquara, São Paulo, BrazilKU Leuven-University of Leuven, Department of Pharmaceutical and Pharmacological Sciences, Pharmaceutical Analysis, Leuven, BelgiumUNESP-Univ Estadual Paulista, Faculdade de Ciências Farmacêuticas, Araraquara, São Paulo, BrazilAn innovative method is validated for the analysis of ertapenem sodium by capillary electrophoresis using potassium phosphate buffer 10 mM pH 7 and 15 kV voltage, in the concentration range of 70 to 120 μg mL−1. Ertapenem had a migration time of 3.15 minutes and the linearity curve was y = 2281.7 x - 24495 with a R2 = 0.9994. Thus, we propose a routine analysis method that meets the principles of green analytical chemistry for the routine analysis of ertapenem sodium by capillary electrophoresis.http://dx.doi.org/10.1155/2019/1456313
spellingShingle Tahisa Marcela Pedroso
Ann Van Schepdael
Hérida Regina Nunes Salgado
Application of the Principles of Green Chemistry for the Development of a New and Sensitive Method for Analysis of Ertapenem Sodium by Capillary Electrophoresis
International Journal of Analytical Chemistry
title Application of the Principles of Green Chemistry for the Development of a New and Sensitive Method for Analysis of Ertapenem Sodium by Capillary Electrophoresis
title_full Application of the Principles of Green Chemistry for the Development of a New and Sensitive Method for Analysis of Ertapenem Sodium by Capillary Electrophoresis
title_fullStr Application of the Principles of Green Chemistry for the Development of a New and Sensitive Method for Analysis of Ertapenem Sodium by Capillary Electrophoresis
title_full_unstemmed Application of the Principles of Green Chemistry for the Development of a New and Sensitive Method for Analysis of Ertapenem Sodium by Capillary Electrophoresis
title_short Application of the Principles of Green Chemistry for the Development of a New and Sensitive Method for Analysis of Ertapenem Sodium by Capillary Electrophoresis
title_sort application of the principles of green chemistry for the development of a new and sensitive method for analysis of ertapenem sodium by capillary electrophoresis
url http://dx.doi.org/10.1155/2019/1456313
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