sTREM2 is associated with amyloid‐related p‐tau increases and glucose hypermetabolism in Alzheimer's disease
Abstract Microglial activation occurs early in Alzheimer's disease (AD) and previous studies reported both detrimental and protective effects of microglia on AD progression. Here, we used CSF sTREM2 to investigate disease stage‐dependent drivers of microglial activation and to determine downstr...
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| Main Authors: | Davina Biel, Marc Suárez‐Calvet, Paul Hager, Anna Rubinski, Anna Dewenter, Anna Steward, Sebastian Roemer, Michael Ewers, Christian Haass, Matthias Brendel, Nicolai Franzmeier, for the Alzheimer's Disease Neuroimaging Initiative (ADNI) |
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| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2023-01-01
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| Series: | EMBO Molecular Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.15252/emmm.202216987 |
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