Local Application of a New Chalconic Derivative (Chalcone T4) Reduces Inflammation and Oxidative Stress in a Periodontitis Model in Rats

Local Application of a New Chalconic Derivative (Chalcone T4) Reduces Inflammation and Oxidative Stress in a Periodontitis Model in Rats

Chalcones are phenolic compounds with biological properties. This study had the aim to evaluate the effects of topical administration of a new synthetic chalcone, Chalcone T4, in an animal model of periodontitis induced by ligature. Forty rats were distributed in the following experimental groups: n...

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Main Authors: Angelo Constantino Camilli, Mariely Araújo de Godoi, Vitória Bonan Costa, Natalie Aparecida Rodrigues Fernandes, Giovani Cirelli, Larissa Kely Faustino da Silva, Letícia Ribeiro Assis, Luis Octavio Regasini, Morgana Rodrigues Guimarães-Stabili
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Antioxidants
Subjects:
periodontitis
chalcone
topical application
antioxidant activity
Online Access:https://www.mdpi.com/2076-3921/13/10/1192
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