Bone Cement Implantation Syndrome in the Perioperative Period of Large Joint Endoprosthesis
Objective: to enhance the efficiency of diagnosis of and intensive therapy for bone cement implantation syndrome in the perioperative period of endoprosthesis of large joints of the lower extremity.Subjects and methods: A study group comprised 18 patients who received standard perioperative intensiv...
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Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
2007-08-01
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| Series: | Общая реаниматология |
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| Online Access: | https://www.reanimatology.com/rmt/article/view/975 |
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| author | I. A. Tomashevsky Ye. V. Grigoryev A. S. Razumov G. A. Li G. V. Vavin |
| author_facet | I. A. Tomashevsky Ye. V. Grigoryev A. S. Razumov G. A. Li G. V. Vavin |
| author_sort | I. A. Tomashevsky |
| collection | DOAJ |
| description | Objective: to enhance the efficiency of diagnosis of and intensive therapy for bone cement implantation syndrome in the perioperative period of endoprosthesis of large joints of the lower extremity.Subjects and methods: A study group comprised 18 patients who received standard perioperative intensive therapy for the bone cement implantation syndrome. A control group included 22 patients in whom perioperative correction of hemostatic disorders was made, by including 6% solution into the infusion program of second-generation hydroxyethyl starches (200/0.5) and by postoperatively administering low molecular-weight heparins. To evaluate the state of the basic hemostatic links, the classical laboratory parameters were determined, as described by Z. S. Barkagan, et al. Concurrent with the determination of the classical parameters, an integral estimate was made by rapid blood viscosimetry.Results. Impairments of basic hemostatic links in the bone cement implantation syndrome are characterized by the development of prethrombosis. Rapid blood viscometric parameters, such as the rate of spontaneous platelet aggregation, the onset of clotting, the constants of thrombin, blood clotting, total blood clotting, a fibrin-platelet constant, and the cumulative rate of clot retraction and lysis, correlate with classical biochemical parameters.Conclusion. The pathogenetically warranted use of a combination of low molecular-weight heparin and second-generation hydrox-yethyl starch enhances the efficiency of correction of perioperative impairments of the basic hemostatic links in the cement endoprosthetic replacement of large joints of the lower extremity. |
| format | Article |
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| institution | Kabale University |
| issn | 1813-9779 2411-7110 |
| language | English |
| publishDate | 2007-08-01 |
| publisher | Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia |
| record_format | Article |
| series | Общая реаниматология |
| spelling | doaj-art-ea62af968d2d4b67924ed54b544434a02025-08-20T03:59:40ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102007-08-0134939710.15360/1813-9779-2007-4-93-97975Bone Cement Implantation Syndrome in the Perioperative Period of Large Joint EndoprosthesisI. A. Tomashevsky0Ye. V. Grigoryev1A. S. Razumov2G. A. Li3G. V. Vavin4Kemerovo State Medical Academy, Russian Agency for Health Care, M. A. Podgorbunsky City Clinical Hospital Three, Kemerovo, Branch of the Research Institute of General Reanimatology, Russian Academy of Medical Sciences, NovokuznetskKemerovo State Medical Academy, Russian Agency for Health Care, M. A. Podgorbunsky City Clinical Hospital Three, Kemerovo, Branch of the Research Institute of General Reanimatology, Russian Academy of Medical Sciences, NovokuznetskKemerovo State Medical Academy, Russian Agency for Health Care, M. A. Podgorbunsky City Clinical Hospital Three, Kemerovo, Branch of the Research Institute of General Reanimatology, Russian Academy of Medical Sciences, NovokuznetskKemerovo State Medical Academy, Russian Agency for Health Care, M. A. Podgorbunsky City Clinical Hospital Three, Kemerovo, Branch of the Research Institute of General Reanimatology, Russian Academy of Medical Sciences, NovokuznetskKemerovo State Medical Academy, Russian Agency for Health Care, M. A. Podgorbunsky City Clinical Hospital Three, Kemerovo, Branch of the Research Institute of General Reanimatology, Russian Academy of Medical Sciences, NovokuznetskObjective: to enhance the efficiency of diagnosis of and intensive therapy for bone cement implantation syndrome in the perioperative period of endoprosthesis of large joints of the lower extremity.Subjects and methods: A study group comprised 18 patients who received standard perioperative intensive therapy for the bone cement implantation syndrome. A control group included 22 patients in whom perioperative correction of hemostatic disorders was made, by including 6% solution into the infusion program of second-generation hydroxyethyl starches (200/0.5) and by postoperatively administering low molecular-weight heparins. To evaluate the state of the basic hemostatic links, the classical laboratory parameters were determined, as described by Z. S. Barkagan, et al. Concurrent with the determination of the classical parameters, an integral estimate was made by rapid blood viscosimetry.Results. Impairments of basic hemostatic links in the bone cement implantation syndrome are characterized by the development of prethrombosis. Rapid blood viscometric parameters, such as the rate of spontaneous platelet aggregation, the onset of clotting, the constants of thrombin, blood clotting, total blood clotting, a fibrin-platelet constant, and the cumulative rate of clot retraction and lysis, correlate with classical biochemical parameters.Conclusion. The pathogenetically warranted use of a combination of low molecular-weight heparin and second-generation hydrox-yethyl starch enhances the efficiency of correction of perioperative impairments of the basic hemostatic links in the cement endoprosthetic replacement of large joints of the lower extremity.https://www.reanimatology.com/rmt/article/view/975bone cementhemostasislarge joint endoprosthesisinstrumental diagnosiscorrection |
| spellingShingle | I. A. Tomashevsky Ye. V. Grigoryev A. S. Razumov G. A. Li G. V. Vavin Bone Cement Implantation Syndrome in the Perioperative Period of Large Joint Endoprosthesis Общая реаниматология bone cement hemostasis large joint endoprosthesis instrumental diagnosis correction |
| title | Bone Cement Implantation Syndrome in the Perioperative Period of Large Joint Endoprosthesis |
| title_full | Bone Cement Implantation Syndrome in the Perioperative Period of Large Joint Endoprosthesis |
| title_fullStr | Bone Cement Implantation Syndrome in the Perioperative Period of Large Joint Endoprosthesis |
| title_full_unstemmed | Bone Cement Implantation Syndrome in the Perioperative Period of Large Joint Endoprosthesis |
| title_short | Bone Cement Implantation Syndrome in the Perioperative Period of Large Joint Endoprosthesis |
| title_sort | bone cement implantation syndrome in the perioperative period of large joint endoprosthesis |
| topic | bone cement hemostasis large joint endoprosthesis instrumental diagnosis correction |
| url | https://www.reanimatology.com/rmt/article/view/975 |
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