The need for Open Labs for fostering interdisciplinarities in Modern Chemistry. Biocatalysis: a necessary tool for synthetic chemists
Among the different fields of chemical approaches available to the synthetic chemists, biocatalysis is only being slowly adopted, especially due to a lack of know-how and practical experience. However, enzymatic catalysis is a mature technology, and this should encourage more chemists to take furthe...
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| Language: | English |
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Académie des sciences
2024-02-01
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| Series: | Comptes Rendus. Chimie |
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| Online Access: | https://comptes-rendus.academie-sciences.fr/chimie/articles/10.5802/crchim.281/ |
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| author | Martin, Juliette |
| author_facet | Martin, Juliette |
| author_sort | Martin, Juliette |
| collection | DOAJ |
| description | Among the different fields of chemical approaches available to the synthetic chemists, biocatalysis is only being slowly adopted, especially due to a lack of know-how and practical experience. However, enzymatic catalysis is a mature technology, and this should encourage more chemists to take further ownership and expand applications in modern chemistry.In the industrial sector, some pharmaceutical companies have been pioneers in the use and acceptance of biocatalysis for the unique properties that enzymes can deliver. In this article, the key concepts for biocatalysis applications will be addressed including some recommendations to new practitioners. Some industrial examples will be presented, such as polycyclization, regioselective acylation, alkene asymmetric bioreduction, meso desymmetrization, kinetic resolution and aldolization. Biocatalysis provides economic and environmental benefits, its awareness should be enhanced, especially in a momentum of conducting hybrid approaches and multicatalysis. Open your Labs! |
| format | Article |
| id | doaj-art-ea5f18055d8f43b0847dd52c26958fbd |
| institution | Kabale University |
| issn | 1878-1543 |
| language | English |
| publishDate | 2024-02-01 |
| publisher | Académie des sciences |
| record_format | Article |
| series | Comptes Rendus. Chimie |
| spelling | doaj-art-ea5f18055d8f43b0847dd52c26958fbd2025-02-07T13:40:29ZengAcadémie des sciencesComptes Rendus. Chimie1878-15432024-02-0127S29911510.5802/crchim.28110.5802/crchim.281The need for Open Labs for fostering interdisciplinarities in Modern Chemistry. Biocatalysis: a necessary tool for synthetic chemistsMartin, Juliette0https://orcid.org/0000-0003-1756-848X70 Allée Graham Bell, 30035 Nîmes – SEQENS, FranceAmong the different fields of chemical approaches available to the synthetic chemists, biocatalysis is only being slowly adopted, especially due to a lack of know-how and practical experience. However, enzymatic catalysis is a mature technology, and this should encourage more chemists to take further ownership and expand applications in modern chemistry.In the industrial sector, some pharmaceutical companies have been pioneers in the use and acceptance of biocatalysis for the unique properties that enzymes can deliver. In this article, the key concepts for biocatalysis applications will be addressed including some recommendations to new practitioners. Some industrial examples will be presented, such as polycyclization, regioselective acylation, alkene asymmetric bioreduction, meso desymmetrization, kinetic resolution and aldolization. Biocatalysis provides economic and environmental benefits, its awareness should be enhanced, especially in a momentum of conducting hybrid approaches and multicatalysis. Open your Labs!https://comptes-rendus.academie-sciences.fr/chimie/articles/10.5802/crchim.281/BiocatalysisEnzymesCatalysisAsymmetric synthesisSustainabilityGreen chemistry |
| spellingShingle | Martin, Juliette The need for Open Labs for fostering interdisciplinarities in Modern Chemistry. Biocatalysis: a necessary tool for synthetic chemists Comptes Rendus. Chimie Biocatalysis Enzymes Catalysis Asymmetric synthesis Sustainability Green chemistry |
| title | The need for Open Labs for fostering interdisciplinarities in Modern Chemistry. Biocatalysis: a necessary tool for synthetic chemists |
| title_full | The need for Open Labs for fostering interdisciplinarities in Modern Chemistry. Biocatalysis: a necessary tool for synthetic chemists |
| title_fullStr | The need for Open Labs for fostering interdisciplinarities in Modern Chemistry. Biocatalysis: a necessary tool for synthetic chemists |
| title_full_unstemmed | The need for Open Labs for fostering interdisciplinarities in Modern Chemistry. Biocatalysis: a necessary tool for synthetic chemists |
| title_short | The need for Open Labs for fostering interdisciplinarities in Modern Chemistry. Biocatalysis: a necessary tool for synthetic chemists |
| title_sort | need for open labs for fostering interdisciplinarities in modern chemistry biocatalysis a necessary tool for synthetic chemists |
| topic | Biocatalysis Enzymes Catalysis Asymmetric synthesis Sustainability Green chemistry |
| url | https://comptes-rendus.academie-sciences.fr/chimie/articles/10.5802/crchim.281/ |
| work_keys_str_mv | AT martinjuliette theneedforopenlabsforfosteringinterdisciplinaritiesinmodernchemistrybiocatalysisanecessarytoolforsyntheticchemists AT martinjuliette needforopenlabsforfosteringinterdisciplinaritiesinmodernchemistrybiocatalysisanecessarytoolforsyntheticchemists |