Oligomeric hyaluronic acid-modified liposomes effectively improved skin permeability and anti-ageing activity of ellagic acid

Oligomeric hyaluronic acid-modified liposomes effectively improved skin permeability and anti-ageing activity of ellagic acid

Abstract To overcome natural skin barrier, deliver ellagic acid (EA) to the dermis, and promote its anti-ageing efficacy, oligomeric hyaluronic acid (HA) modified EA-loaded liposomes (EA-HA-L) were constructed via self-synthesized different molecular weights of HA linked cholesterol (HA-Chol), and t...

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Bibliographic Details
Main Authors: Xiaojing Yang, Kaiyuan Miao, Zhiwei Chen, Yan Meng, Jie Xiang, Chiqing Chen, Xinyan Chen, Zhaohua Shi
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Ellagic acid
Hyaluronic acid-modified cholesterol
Liposomes
Skin permeability
Anti-ageing
Online Access:https://doi.org/10.1038/s41598-025-06948-0
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