Intractable Chronic Vulval Ulceration Presenting as Immune Reconstitution Inflammatory Syndrome in a Treatment-Failure Patient: A Case Observation

HIV-1 treatment-failure patients are increasingly being initiated on second-line antiretroviral therapy. The case we describe is of a treatment-failure patient who developed intractable chronic vulval ulceration presenting as immune reconstitution inflammatory syndrome (IRIS), following complete vir...

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Main Authors: Christine Katusiime, Ponsiano Ocama, Andrew Kambugu
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Case Reports in Obstetrics and Gynecology
Online Access:http://dx.doi.org/10.1155/2011/896964
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author Christine Katusiime
Ponsiano Ocama
Andrew Kambugu
author_facet Christine Katusiime
Ponsiano Ocama
Andrew Kambugu
author_sort Christine Katusiime
collection DOAJ
description HIV-1 treatment-failure patients are increasingly being initiated on second-line antiretroviral therapy. The case we describe is of a treatment-failure patient who developed intractable chronic vulval ulceration presenting as immune reconstitution inflammatory syndrome (IRIS), following complete viral suppression with second-line highly active antiretroviral treatment (HAART). To the best of our knowledge, this is the first reported case of intractable vulval ulceration IRIS in an HIV-1 treatment-failure patient.
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2090-6692
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spelling doaj-art-ea3a82ec9b2f4e528f12506f4de98cb82025-08-20T02:21:57ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922011-01-01201110.1155/2011/896964896964Intractable Chronic Vulval Ulceration Presenting as Immune Reconstitution Inflammatory Syndrome in a Treatment-Failure Patient: A Case ObservationChristine Katusiime0Ponsiano Ocama1Andrew Kambugu2Department of Prevention, Care and Treatment, Infectious Diseases Institute, Makerere University College of Health Sciences, Kampala, UgandaDepartment of Medicine, Makerere University College of Health Sciences, Kampala, UgandaDepartment of Prevention, Care and Treatment, Infectious Diseases Institute, Makerere University College of Health Sciences, Kampala, UgandaHIV-1 treatment-failure patients are increasingly being initiated on second-line antiretroviral therapy. The case we describe is of a treatment-failure patient who developed intractable chronic vulval ulceration presenting as immune reconstitution inflammatory syndrome (IRIS), following complete viral suppression with second-line highly active antiretroviral treatment (HAART). To the best of our knowledge, this is the first reported case of intractable vulval ulceration IRIS in an HIV-1 treatment-failure patient.http://dx.doi.org/10.1155/2011/896964
spellingShingle Christine Katusiime
Ponsiano Ocama
Andrew Kambugu
Intractable Chronic Vulval Ulceration Presenting as Immune Reconstitution Inflammatory Syndrome in a Treatment-Failure Patient: A Case Observation
Case Reports in Obstetrics and Gynecology
title Intractable Chronic Vulval Ulceration Presenting as Immune Reconstitution Inflammatory Syndrome in a Treatment-Failure Patient: A Case Observation
title_full Intractable Chronic Vulval Ulceration Presenting as Immune Reconstitution Inflammatory Syndrome in a Treatment-Failure Patient: A Case Observation
title_fullStr Intractable Chronic Vulval Ulceration Presenting as Immune Reconstitution Inflammatory Syndrome in a Treatment-Failure Patient: A Case Observation
title_full_unstemmed Intractable Chronic Vulval Ulceration Presenting as Immune Reconstitution Inflammatory Syndrome in a Treatment-Failure Patient: A Case Observation
title_short Intractable Chronic Vulval Ulceration Presenting as Immune Reconstitution Inflammatory Syndrome in a Treatment-Failure Patient: A Case Observation
title_sort intractable chronic vulval ulceration presenting as immune reconstitution inflammatory syndrome in a treatment failure patient a case observation
url http://dx.doi.org/10.1155/2011/896964
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AT andrewkambugu intractablechronicvulvalulcerationpresentingasimmunereconstitutioninflammatorysyndromeinatreatmentfailurepatientacaseobservation