Acute flaccid paralysis surveillance data analysis, Sana’a City, Yemen, 2012-2021: A retrospective descriptive analysis

Background: WHO certified Yemen polio-free in 2009. Outbreaks of circulating Vaccine Derived Polioviruses (cVDPV) threaten the eventual eradication of all polioviruses. In Yemen, two outbreaks of cVDPV type 1 and 2 were reported in 2020 and 2021-2022, respectively. This study aimed to describe trend...

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Main Authors: Lamya Abdo Al Aroomi, Labiba Saeed Anam, Mutahar Ahmed AL Qassimi, Faten Hamid Ezzadeen
Format: Article
Language:English
Published: African Field Epidemiology Network 2025-04-01
Series:Journal of Interventional Epidemiology and Public Health
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Online Access:https://afenet-journal.org/acute-flaccid-paralysis-surveillance-data-analysis-sanaa-city-yemen-2012-2021-a-retrospective-descriptive-analysis-research/
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author Lamya Abdo Al Aroomi
Labiba Saeed Anam
Mutahar Ahmed AL Qassimi
Faten Hamid Ezzadeen
author_facet Lamya Abdo Al Aroomi
Labiba Saeed Anam
Mutahar Ahmed AL Qassimi
Faten Hamid Ezzadeen
author_sort Lamya Abdo Al Aroomi
collection DOAJ
description Background: WHO certified Yemen polio-free in 2009. Outbreaks of circulating Vaccine Derived Polioviruses (cVDPV) threaten the eventual eradication of all polioviruses. In Yemen, two outbreaks of cVDPV type 1 and 2 were reported in 2020 and 2021-2022, respectively. This study aimed to describe trends and characteristics of AFP cases in Sanaa city over the last ten years, from 2012 to 2021. Methods: This cross-sectional study involved retrospective descriptive analysis of surveillance data. All AFP cases reported to the AFP Surveillance System at the Ministry of Public Health and Population between January 2012 and December 2021 were included. Results: During the ten years’ period, a total of 593 cases of AFP were reported in Sana’a City; none of which was confirmed as poliomyelitis. 56% of AFP cases were males, and 60% aged five years or younger. More than half (61%) of cases had received 4 doses or more of OPV. The predominant clinical feature was fever (79%). Paralysis progressed within 3 days of onset in 437 (74%) cases, which was asymmetrical in 202 (34%) cases. The annual incidence of non-polio AFP ranged from 2.6/100,000 to 4.9/100,000 (mean: 3.5/100,000), which met the WHO target. Regarding sample adequacy, we found that in 2017, the sample adequacy fell short of the expected minimal (80%) level, though all districts met the WHO target (>80%) except in At Tahrir District (77%). Conclusions: The AFP surveillance system has improved over the past 10 years in Sana’a city. However, strengthening the two main indicators of AFP surveillance, especially sample adequacy, is recommended. It is advisable to establish a national laboratory that adheres to WHO-recommended procedures for detecting polioviruses in stool samples. Because zero doses were reported among 12% of AFP cases, maintaining high coverage through routine immunization and supporting supplementary immunization activities is crucial to ensure that most children are vaccinated, thereby contributing to the eradication of polio.
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spelling doaj-art-ea34fff404824143805b73ede3c33cd62025-08-20T02:25:09ZengAfrican Field Epidemiology NetworkJournal of Interventional Epidemiology and Public Health2664-28242025-04-01821https://doi.org/10.37432/jieph-d-24-02043Acute flaccid paralysis surveillance data analysis, Sana’a City, Yemen, 2012-2021: A retrospective descriptive analysisLamya Abdo Al Aroomi0Labiba Saeed Anam1Mutahar Ahmed AL Qassimi2Faten Hamid Ezzadeen3Yemen Field Epidemiology Training Program (YFETP), Ministry of Public Health and Population, Sana’a, YemenYemen Field Epidemiology Training Program (YFETP), Ministry of Public Health and Population, Sana’a, YemenAFP Surveillance Program, Ministry of Public Health and Population, Sana’a, YemenAFP Surveillance Program, Ministry of Public Health and Population, Sana’a, YemenBackground: WHO certified Yemen polio-free in 2009. Outbreaks of circulating Vaccine Derived Polioviruses (cVDPV) threaten the eventual eradication of all polioviruses. In Yemen, two outbreaks of cVDPV type 1 and 2 were reported in 2020 and 2021-2022, respectively. This study aimed to describe trends and characteristics of AFP cases in Sanaa city over the last ten years, from 2012 to 2021. Methods: This cross-sectional study involved retrospective descriptive analysis of surveillance data. All AFP cases reported to the AFP Surveillance System at the Ministry of Public Health and Population between January 2012 and December 2021 were included. Results: During the ten years’ period, a total of 593 cases of AFP were reported in Sana’a City; none of which was confirmed as poliomyelitis. 56% of AFP cases were males, and 60% aged five years or younger. More than half (61%) of cases had received 4 doses or more of OPV. The predominant clinical feature was fever (79%). Paralysis progressed within 3 days of onset in 437 (74%) cases, which was asymmetrical in 202 (34%) cases. The annual incidence of non-polio AFP ranged from 2.6/100,000 to 4.9/100,000 (mean: 3.5/100,000), which met the WHO target. Regarding sample adequacy, we found that in 2017, the sample adequacy fell short of the expected minimal (80%) level, though all districts met the WHO target (>80%) except in At Tahrir District (77%). Conclusions: The AFP surveillance system has improved over the past 10 years in Sana’a city. However, strengthening the two main indicators of AFP surveillance, especially sample adequacy, is recommended. It is advisable to establish a national laboratory that adheres to WHO-recommended procedures for detecting polioviruses in stool samples. Because zero doses were reported among 12% of AFP cases, maintaining high coverage through routine immunization and supporting supplementary immunization activities is crucial to ensure that most children are vaccinated, thereby contributing to the eradication of polio.https://afenet-journal.org/acute-flaccid-paralysis-surveillance-data-analysis-sanaa-city-yemen-2012-2021-a-retrospective-descriptive-analysis-research/acute flaccid paralysis (afp)surveillanceanalysissana’a cityyemen
spellingShingle Lamya Abdo Al Aroomi
Labiba Saeed Anam
Mutahar Ahmed AL Qassimi
Faten Hamid Ezzadeen
Acute flaccid paralysis surveillance data analysis, Sana’a City, Yemen, 2012-2021: A retrospective descriptive analysis
Journal of Interventional Epidemiology and Public Health
acute flaccid paralysis (afp)
surveillance
analysis
sana’a city
yemen
title Acute flaccid paralysis surveillance data analysis, Sana’a City, Yemen, 2012-2021: A retrospective descriptive analysis
title_full Acute flaccid paralysis surveillance data analysis, Sana’a City, Yemen, 2012-2021: A retrospective descriptive analysis
title_fullStr Acute flaccid paralysis surveillance data analysis, Sana’a City, Yemen, 2012-2021: A retrospective descriptive analysis
title_full_unstemmed Acute flaccid paralysis surveillance data analysis, Sana’a City, Yemen, 2012-2021: A retrospective descriptive analysis
title_short Acute flaccid paralysis surveillance data analysis, Sana’a City, Yemen, 2012-2021: A retrospective descriptive analysis
title_sort acute flaccid paralysis surveillance data analysis sana a city yemen 2012 2021 a retrospective descriptive analysis
topic acute flaccid paralysis (afp)
surveillance
analysis
sana’a city
yemen
url https://afenet-journal.org/acute-flaccid-paralysis-surveillance-data-analysis-sanaa-city-yemen-2012-2021-a-retrospective-descriptive-analysis-research/
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