Ascorbic acid and microcirculation in cardiothoracic surgery: a pilot feasibility trial and matched cohort study

Ascorbic acid and microcirculation in cardiothoracic surgery: a pilot feasibility trial and matched cohort study

Abstract Background Ascorbic acid is an essential cofactor of catecholamine synthesis that increases capillary bed density and improves microcirculation perfusion. We hypothesized early ascorbic acid administration in cardiothoracic surgery would preserve the microcirculatory integrity and minimize...

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Bibliographic Details
Main Authors: Patrick M. Wieruszewski, Misty A. Radosevich, Scott D. Nei, Kianoush B. Kashani, Sarah E. Normand, Hartzell V. Schaff, Erica D. Wittwer
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Journal of Cardiothoracic Surgery
Subjects:
Vasoplegia
Vasodilation
Shock
Vitamin C
Cardiopulmonary bypass
Microcirculation
Online Access:https://doi.org/10.1186/s13019-025-03486-8
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