Age-related cerebral changes during different n-back tasks: a functional near-infrared spectroscopy study
BackgroundThe n-back task is a widely used paradigm to assess working memory and is commonly applied in research on age-related cognitive decline. However, studies utilizing functional near-infrared spectroscopy (fNIRS) to explore this area are limited.ObjectiveThis study aims to investigate age-rel...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2024-10-01
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| Series: | Frontiers in Aging Neuroscience |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fnagi.2024.1437587/full |
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| Summary: | BackgroundThe n-back task is a widely used paradigm to assess working memory and is commonly applied in research on age-related cognitive decline. However, studies utilizing functional near-infrared spectroscopy (fNIRS) to explore this area are limited.ObjectiveThis study aims to investigate age-related differences in brain activation during the n-back task using fNIRS.MethodsfNIRS data were collected from 18 elderly and 19 young participants while performing different n-back tasks. Brain activation patterns and peripheral performance were compared between the two groups.ResultsSignificant differences in brain activation patterns were observed between elderly and young participants. Under the 3-back condition, the older group exhibited reduced activation in brain regions adjacent to prefrontal cognitive areas compared to the younger group. Additionally, the older group’s performance plateaued at the 2-back level, along with a decline in prefrontal activation.ConclusionThese findings may suggest potential markers for cognitive decline, providing a new target for future screening. |
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| ISSN: | 1663-4365 |