THE SEVERE COURSE OF DRUG THERAPY-RESISTANT ANKYLOSING SPONDYLITIS
At present, there is more and more evidence in rheumatology on the factors influencing the efficacy of biological agents (BAs), and there is no generally accepted algorithm for managing patients resistant to standard therapy. The paper describes three patients with ankylosing spondylitis (AS) who we...
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| Format: | Article |
| Language: | Russian |
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IMA PRESS LLC
2020-04-01
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| Series: | Научно-практическая ревматология |
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| Online Access: | https://rsp.mediar-press.net/rsp/article/view/2882 |
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| author | D. G. Rumyantseva M. V. Podryadnova O. A. Rumyantseva M. M. Urumova Sh. Erdes |
| author_facet | D. G. Rumyantseva M. V. Podryadnova O. A. Rumyantseva M. M. Urumova Sh. Erdes |
| author_sort | D. G. Rumyantseva |
| collection | DOAJ |
| description | At present, there is more and more evidence in rheumatology on the factors influencing the efficacy of biological agents (BAs), and there is no generally accepted algorithm for managing patients resistant to standard therapy. The paper describes three patients with ankylosing spondylitis (AS) who were followed up at the V.A. Nasonova Research Institute of Rheumatology in 2011–2019. All the patients showed a severe course of AS of high clinical and laboratory activities, extra-articular manifestations, and inefficacy of three or more BAs. All the patients share the following symptoms: male gender, early onset of disease, high clinical and laboratory activities, and extra-articular manifestations, such as uveitis and psoriasis. |
| format | Article |
| id | doaj-art-ea243decf0724a66a945f04dc906e17b |
| institution | Kabale University |
| issn | 1995-4484 1995-4492 |
| language | Russian |
| publishDate | 2020-04-01 |
| publisher | IMA PRESS LLC |
| record_format | Article |
| series | Научно-практическая ревматология |
| spelling | doaj-art-ea243decf0724a66a945f04dc906e17b2025-08-20T03:59:30ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922020-04-0158223223710.14412/1995-4484-2020-233-2372605THE SEVERE COURSE OF DRUG THERAPY-RESISTANT ANKYLOSING SPONDYLITISD. G. Rumyantseva0M. V. Podryadnova1O. A. Rumyantseva2M. M. Urumova3Sh. Erdes4V.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyAt present, there is more and more evidence in rheumatology on the factors influencing the efficacy of biological agents (BAs), and there is no generally accepted algorithm for managing patients resistant to standard therapy. The paper describes three patients with ankylosing spondylitis (AS) who were followed up at the V.A. Nasonova Research Institute of Rheumatology in 2011–2019. All the patients showed a severe course of AS of high clinical and laboratory activities, extra-articular manifestations, and inefficacy of three or more BAs. All the patients share the following symptoms: male gender, early onset of disease, high clinical and laboratory activities, and extra-articular manifestations, such as uveitis and psoriasis.https://rsp.mediar-press.net/rsp/article/view/2882ankylosing spondylitisbiological agentshigh activityinefficacy of biological agents |
| spellingShingle | D. G. Rumyantseva M. V. Podryadnova O. A. Rumyantseva M. M. Urumova Sh. Erdes THE SEVERE COURSE OF DRUG THERAPY-RESISTANT ANKYLOSING SPONDYLITIS Научно-практическая ревматология ankylosing spondylitis biological agents high activity inefficacy of biological agents |
| title | THE SEVERE COURSE OF DRUG THERAPY-RESISTANT ANKYLOSING SPONDYLITIS |
| title_full | THE SEVERE COURSE OF DRUG THERAPY-RESISTANT ANKYLOSING SPONDYLITIS |
| title_fullStr | THE SEVERE COURSE OF DRUG THERAPY-RESISTANT ANKYLOSING SPONDYLITIS |
| title_full_unstemmed | THE SEVERE COURSE OF DRUG THERAPY-RESISTANT ANKYLOSING SPONDYLITIS |
| title_short | THE SEVERE COURSE OF DRUG THERAPY-RESISTANT ANKYLOSING SPONDYLITIS |
| title_sort | severe course of drug therapy resistant ankylosing spondylitis |
| topic | ankylosing spondylitis biological agents high activity inefficacy of biological agents |
| url | https://rsp.mediar-press.net/rsp/article/view/2882 |
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