HECTD2 is associated with susceptibility to mouse and human prion disease.
Prion diseases are fatal transmissible neurodegenerative disorders, which include Scrapie, Bovine Spongiform Encephalopathy (BSE), Creutzfeldt-Jakob Disease (CJD), and kuru. They are characterised by a prolonged clinically silent incubation period, variation in which is determined by many factors, i...
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| Main Authors: | Sarah E Lloyd, Emma G Maytham, Hirva Pota, Julia Grizenkova, Eleni Molou, James Uphill, Holger Hummerich, Jerome Whitfield, Michael P Alpers, Simon Mead, John Collinge |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2009-02-01
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| Series: | PLoS Genetics |
| Online Access: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1000383&type=printable |
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