METABOLIC DISTURBANCES IN THE FUTURE DEVELOPMENT AND PROGRESSION OF ARTERIAL HYPERTENSION IN YOUNG MEN

Objective: to reveal carbohydrate and lipid metabolic disturbances and their possible importance in examined young men with early arterial hypertension (AH). Subjects and methods. A total of 130 men aged 40.3 ± 4.3 years were examined. There were 3 patient groups: stage I hypertensive disease with a...

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Main Authors: A. V. Gordienko, M. A. Mirokhina, V. T. Dydyshko, D. Yu. Serdyukov, A. S. Fedorova
Format: Article
Language:Russian
Published: ABV-press 2015-08-01
Series:Klinicist
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Online Access:https://klinitsist.abvpress.ru/Klin/article/view/191
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author A. V. Gordienko
M. A. Mirokhina
V. T. Dydyshko
D. Yu. Serdyukov
A. S. Fedorova
author_facet A. V. Gordienko
M. A. Mirokhina
V. T. Dydyshko
D. Yu. Serdyukov
A. S. Fedorova
author_sort A. V. Gordienko
collection DOAJ
description Objective: to reveal carbohydrate and lipid metabolic disturbances and their possible importance in examined young men with early arterial hypertension (AH). Subjects and methods. A total of 130 men aged 40.3 ± 4.3 years were examined. There were 3 patient groups: stage I hypertensive disease with a history of AH (n = 61); primarily diagnosed hypertensive disease without evidence of long-term AH (n = 39); a control group noncardiovascular diseases (n = 30). Results. The patients with long-term AH were more commonly found to have a compromised history of cardiovascular diseases and type 2 diabetes mellitus, signs of insulin resistance and subclinical atherosclerosis than those with the primarily diagnosed disease and the control group. Conclusion. Carbohydrate and lipid metabolic disturbances are latent in young men with long-term AH. Both 2and 1-hour oral glucose tolerance tests are recommended for the early diagnosis of glycemic disorders in the above patient cohort.
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spelling doaj-art-ea21b68b92714920a8a28b9decbf7e2b2025-08-20T03:02:18ZrusABV-pressKlinicist1818-83382015-08-0192232710.17650/1818-8338-2015-9-2-23-27192METABOLIC DISTURBANCES IN THE FUTURE DEVELOPMENT AND PROGRESSION OF ARTERIAL HYPERTENSION IN YOUNG MENA. V. Gordienko0M. A. Mirokhina1V. T. Dydyshko2D. Yu. Serdyukov3A. S. Fedorova4S.M. Kirov Military Medical Academy, Ministry of Defense of Russia; 6 Academician Lebedev St., Saint Petersburg, 194044, RussiaS.M. Kirov Military Medical Academy, Ministry of Defense of Russia; 6 Academician Lebedev St., Saint Petersburg, 194044, RussiaS.M. Kirov Military Medical Academy, Ministry of Defense of Russia; 6 Academician Lebedev St., Saint Petersburg, 194044, RussiaS.M. Kirov Military Medical Academy, Ministry of Defense of Russia; 6 Academician Lebedev St., Saint Petersburg, 194044, RussiaS.M. Kirov Military Medical Academy, Ministry of Defense of Russia; 6 Academician Lebedev St., Saint Petersburg, 194044, RussiaObjective: to reveal carbohydrate and lipid metabolic disturbances and their possible importance in examined young men with early arterial hypertension (AH). Subjects and methods. A total of 130 men aged 40.3 ± 4.3 years were examined. There were 3 patient groups: stage I hypertensive disease with a history of AH (n = 61); primarily diagnosed hypertensive disease without evidence of long-term AH (n = 39); a control group noncardiovascular diseases (n = 30). Results. The patients with long-term AH were more commonly found to have a compromised history of cardiovascular diseases and type 2 diabetes mellitus, signs of insulin resistance and subclinical atherosclerosis than those with the primarily diagnosed disease and the control group. Conclusion. Carbohydrate and lipid metabolic disturbances are latent in young men with long-term AH. Both 2and 1-hour oral glucose tolerance tests are recommended for the early diagnosis of glycemic disorders in the above patient cohort.https://klinitsist.abvpress.ru/Klin/article/view/191arterial hypertensionhypertensive diseaseearly lipid and carbohydrate metabolic disorderstandard glucose tolerance testpostprandial glycemiaprediabetesinsulin resistancedyslipidemiaapolipoproteinssubclinical atherosclerosis
spellingShingle A. V. Gordienko
M. A. Mirokhina
V. T. Dydyshko
D. Yu. Serdyukov
A. S. Fedorova
METABOLIC DISTURBANCES IN THE FUTURE DEVELOPMENT AND PROGRESSION OF ARTERIAL HYPERTENSION IN YOUNG MEN
Klinicist
arterial hypertension
hypertensive disease
early lipid and carbohydrate metabolic disorder
standard glucose tolerance test
postprandial glycemia
prediabetes
insulin resistance
dyslipidemia
apolipoproteins
subclinical atherosclerosis
title METABOLIC DISTURBANCES IN THE FUTURE DEVELOPMENT AND PROGRESSION OF ARTERIAL HYPERTENSION IN YOUNG MEN
title_full METABOLIC DISTURBANCES IN THE FUTURE DEVELOPMENT AND PROGRESSION OF ARTERIAL HYPERTENSION IN YOUNG MEN
title_fullStr METABOLIC DISTURBANCES IN THE FUTURE DEVELOPMENT AND PROGRESSION OF ARTERIAL HYPERTENSION IN YOUNG MEN
title_full_unstemmed METABOLIC DISTURBANCES IN THE FUTURE DEVELOPMENT AND PROGRESSION OF ARTERIAL HYPERTENSION IN YOUNG MEN
title_short METABOLIC DISTURBANCES IN THE FUTURE DEVELOPMENT AND PROGRESSION OF ARTERIAL HYPERTENSION IN YOUNG MEN
title_sort metabolic disturbances in the future development and progression of arterial hypertension in young men
topic arterial hypertension
hypertensive disease
early lipid and carbohydrate metabolic disorder
standard glucose tolerance test
postprandial glycemia
prediabetes
insulin resistance
dyslipidemia
apolipoproteins
subclinical atherosclerosis
url https://klinitsist.abvpress.ru/Klin/article/view/191
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