Congenital cytomegalovirus infection: new answers to old problems

Congenital cytomegalovirus infection is one of the most common TORCH infections, characterized by a wide range of clinical manifestations, predominantly with multiple organ lesions and often a disabling course. The result of antenatal infection with cytomegalovirus is a high incidence of congenital...

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Main Authors: Ya. R. Khizhak, H. A. Sarkisyan, A. A. Komarova, V. A. Mironova, I. V. Zhuravleva, M. A. Sarkisyan, P. V. Shumilov
Format: Article
Language:Russian
Published: LLC "Diagnostics and Vaccines" 2024-06-01
Series:Детские инфекции (Москва)
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Online Access:https://detinf.elpub.ru/jour/article/view/946
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author Ya. R. Khizhak
H. A. Sarkisyan
A. A. Komarova
V. A. Mironova
I. V. Zhuravleva
M. A. Sarkisyan
P. V. Shumilov
author_facet Ya. R. Khizhak
H. A. Sarkisyan
A. A. Komarova
V. A. Mironova
I. V. Zhuravleva
M. A. Sarkisyan
P. V. Shumilov
author_sort Ya. R. Khizhak
collection DOAJ
description Congenital cytomegalovirus infection is one of the most common TORCH infections, characterized by a wide range of clinical manifestations, predominantly with multiple organ lesions and often a disabling course. The result of antenatal infection with cytomegalovirus is a high incidence of congenital malformations, often accompanied by disorders such as hearing loss, vision loss, motor and cognitive deficits. Despite the presence of modern domestic clinical recommendations, the study of this pathology remains relevant to the present day. Recently, significant progress has been made in the study of this disease. Every year, new research is conducted on topical issues of diagnosis, treatment and rehabilitation for congenital cytomegalovirus infection. This article provides a review of modern literature, covering the latest data on the molecular basis of pathogenesis, features of clinical manifestations, current approaches to the diagnosis and treatment of congenital cytomegalovirus infection.
format Article
id doaj-art-ea12da4916fe409db228de495a94feaf
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issn 2072-8107
language Russian
publishDate 2024-06-01
publisher LLC "Diagnostics and Vaccines"
record_format Article
series Детские инфекции (Москва)
spelling doaj-art-ea12da4916fe409db228de495a94feaf2025-08-20T02:46:33ZrusLLC "Diagnostics and Vaccines"Детские инфекции (Москва)2072-81072024-06-01232313810.22627/2072-8107-2024-23-2-31-38662Congenital cytomegalovirus infection: new answers to old problemsYa. R. Khizhak0H. A. Sarkisyan1A. A. Komarova2V. A. Mironova3I. V. Zhuravleva4M. A. Sarkisyan5P. V. Shumilov6Pirogov Russian National Research Medical University of the Ministry of Health of the Russian FederationPirogov Russian National Research Medical University of the Ministry of Health of the Russian Federation; Children’s City Clinical Hospital No. 9 named after G.N. SperanskyPirogov Russian National Research Medical University of the Ministry of Health of the Russian FederationPirogov Russian National Research Medical University of the Ministry of Health of the Russian FederationPirogov Russian National Research Medical University of the Ministry of Health of the Russian FederationYevdokimov Moscow State University of Medicine and DentistryPirogov Russian National Research Medical University of the Ministry of Health of the Russian FederationCongenital cytomegalovirus infection is one of the most common TORCH infections, characterized by a wide range of clinical manifestations, predominantly with multiple organ lesions and often a disabling course. The result of antenatal infection with cytomegalovirus is a high incidence of congenital malformations, often accompanied by disorders such as hearing loss, vision loss, motor and cognitive deficits. Despite the presence of modern domestic clinical recommendations, the study of this pathology remains relevant to the present day. Recently, significant progress has been made in the study of this disease. Every year, new research is conducted on topical issues of diagnosis, treatment and rehabilitation for congenital cytomegalovirus infection. This article provides a review of modern literature, covering the latest data on the molecular basis of pathogenesis, features of clinical manifestations, current approaches to the diagnosis and treatment of congenital cytomegalovirus infection.https://detinf.elpub.ru/jour/article/view/946сongenital cmv infectioncytomegalovirusnewborns. ganciclovirhyperimmunoglobulinpregnancysensorineural hearing losscalcificationsneurosonography
spellingShingle Ya. R. Khizhak
H. A. Sarkisyan
A. A. Komarova
V. A. Mironova
I. V. Zhuravleva
M. A. Sarkisyan
P. V. Shumilov
Congenital cytomegalovirus infection: new answers to old problems
Детские инфекции (Москва)
сongenital cmv infection
cytomegalovirus
newborns. ganciclovir
hyperimmunoglobulin
pregnancy
sensorineural hearing loss
calcifications
neurosonography
title Congenital cytomegalovirus infection: new answers to old problems
title_full Congenital cytomegalovirus infection: new answers to old problems
title_fullStr Congenital cytomegalovirus infection: new answers to old problems
title_full_unstemmed Congenital cytomegalovirus infection: new answers to old problems
title_short Congenital cytomegalovirus infection: new answers to old problems
title_sort congenital cytomegalovirus infection new answers to old problems
topic сongenital cmv infection
cytomegalovirus
newborns. ganciclovir
hyperimmunoglobulin
pregnancy
sensorineural hearing loss
calcifications
neurosonography
url https://detinf.elpub.ru/jour/article/view/946
work_keys_str_mv AT yarkhizhak congenitalcytomegalovirusinfectionnewanswerstooldproblems
AT hasarkisyan congenitalcytomegalovirusinfectionnewanswerstooldproblems
AT aakomarova congenitalcytomegalovirusinfectionnewanswerstooldproblems
AT vamironova congenitalcytomegalovirusinfectionnewanswerstooldproblems
AT ivzhuravleva congenitalcytomegalovirusinfectionnewanswerstooldproblems
AT masarkisyan congenitalcytomegalovirusinfectionnewanswerstooldproblems
AT pvshumilov congenitalcytomegalovirusinfectionnewanswerstooldproblems