Combining interferon-γ release assays and metagenomic next-generation sequencing for diagnosis of pulmonary tuberculosis: a retrospective study

Combining interferon-γ release assays and metagenomic next-generation sequencing for diagnosis of pulmonary tuberculosis: a retrospective study

Abstract Background Rapid diagnosis of pulmonary tuberculosis (PTB) is urgently needed. We aimed to improve diagnosis rates by combining tuberculosis-interferon (IFN)-γ release assays (TB-IGRA) with metagenomic next-generation sequencing (mNGS) for PTB diagnosis. Methods A retrospective study of 29...

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Bibliographic Details
Main Authors: Yanyan Liu, Miaohong Fang, Chenxi Yuan, Yi Yang, Liang Yu, Yasheng Li, Lifen Hu, Jiabin Li
Format: Article
Language:English
Published: BMC 2024-11-01
Series:BMC Infectious Diseases
Subjects:
TB-IGRA
Tuberculosis
mNGS
IFN-γ
Sputum smears
Online Access:https://doi.org/10.1186/s12879-024-10206-5
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