Scutellarein ameliorates dextran sulfate sodium-induced ulcerative colitis by inhibiting colonic epithelial cell proinflammation and barrier disruption

Scutellarein ameliorates dextran sulfate sodium-induced ulcerative colitis by inhibiting colonic epithelial cell proinflammation and barrier disruption

IntroductionScutellarein (Scu) is a natural occurring flavonoid found in multiple traditional Chinese medicines such as Oroxylum indicum (L.) Kurz and Scutellaria baicalensis, with various pharmacological activities including anti-inflammation, anti-oxidation and myocardial protection. Here, we inve...

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Bibliographic Details
Main Authors: Qinglian Tang, Haidong Jia, Xu Qin, Zhaowen Lu, Wenjie Huang, Yujing Wang, Zhengyu Cao
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Pharmacology
Subjects:
scutellarein
ulcerative colitis
epithelial barrier integrity
NF-κB
proinflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1479441/full
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