Seemingly Harmless Differentiated Thyroid Carcinoma Presenting as Bone Metastasis

Thyroid carcinoma is the most common endocrine neoplasia. Differentiated thyroid carcinomas (DTCs) represent the majority of cases, which usually follow an indolent clinical course with low mortality rates. The authors describe two cases of well DTC without classic histological poor prognosis featur...

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Main Authors: D. Magalhães, C. Costa, I. Furtado, M. J. Matos, A. P. Santos, H. Duarte, M. Afonso, J. Lobo, I. Torres
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Endocrinology
Online Access:http://dx.doi.org/10.1155/2018/8749075
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author D. Magalhães
C. Costa
I. Furtado
M. J. Matos
A. P. Santos
H. Duarte
M. Afonso
J. Lobo
I. Torres
author_facet D. Magalhães
C. Costa
I. Furtado
M. J. Matos
A. P. Santos
H. Duarte
M. Afonso
J. Lobo
I. Torres
author_sort D. Magalhães
collection DOAJ
description Thyroid carcinoma is the most common endocrine neoplasia. Differentiated thyroid carcinomas (DTCs) represent the majority of cases, which usually follow an indolent clinical course with low mortality rates. The authors describe two cases of well DTC without classic histological poor prognosis features, presenting as extensive and unresectable osteolytic bone metastases. DTCs are considered harmless tumours, due to their benign and silent behaviour. The authors want to underline the importance of clinical awareness during follow-up in cases of DTC, which can be aggressive in presentation and behaviour. Timely identification and diagnosis of these tumours are essential for prompt treatment initiation and improvement of overall survival.
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issn 2090-6501
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publishDate 2018-01-01
publisher Wiley
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series Case Reports in Endocrinology
spelling doaj-art-e9fe6e60114f441e82cb205e801c1f902025-08-20T03:20:40ZengWileyCase Reports in Endocrinology2090-65012090-651X2018-01-01201810.1155/2018/87490758749075Seemingly Harmless Differentiated Thyroid Carcinoma Presenting as Bone MetastasisD. Magalhães0C. Costa1I. Furtado2M. J. Matos3A. P. Santos4H. Duarte5M. Afonso6J. Lobo7I. Torres8Endocrinology, Diabetes and Metabolism Department, Centro Hospitalar São João, Porto, PortugalEndocrinology Department, Instituto Português de Oncologia, Porto, PortugalInternal Medicine Department, Centro Hospitalar do Porto, Porto, PortugalEndocrinology Department, Instituto Português de Oncologia, Porto, PortugalEndocrinology Department, Instituto Português de Oncologia, Porto, PortugalNuclear Medicine Department, Instituto Português de Oncologia, Porto, PortugalPathology Department, Instituto Português de Oncologia, Porto, PortugalPathology Department, Instituto Português de Oncologia, Porto, PortugalEndocrinology Department, Instituto Português de Oncologia, Porto, PortugalThyroid carcinoma is the most common endocrine neoplasia. Differentiated thyroid carcinomas (DTCs) represent the majority of cases, which usually follow an indolent clinical course with low mortality rates. The authors describe two cases of well DTC without classic histological poor prognosis features, presenting as extensive and unresectable osteolytic bone metastases. DTCs are considered harmless tumours, due to their benign and silent behaviour. The authors want to underline the importance of clinical awareness during follow-up in cases of DTC, which can be aggressive in presentation and behaviour. Timely identification and diagnosis of these tumours are essential for prompt treatment initiation and improvement of overall survival.http://dx.doi.org/10.1155/2018/8749075
spellingShingle D. Magalhães
C. Costa
I. Furtado
M. J. Matos
A. P. Santos
H. Duarte
M. Afonso
J. Lobo
I. Torres
Seemingly Harmless Differentiated Thyroid Carcinoma Presenting as Bone Metastasis
Case Reports in Endocrinology
title Seemingly Harmless Differentiated Thyroid Carcinoma Presenting as Bone Metastasis
title_full Seemingly Harmless Differentiated Thyroid Carcinoma Presenting as Bone Metastasis
title_fullStr Seemingly Harmless Differentiated Thyroid Carcinoma Presenting as Bone Metastasis
title_full_unstemmed Seemingly Harmless Differentiated Thyroid Carcinoma Presenting as Bone Metastasis
title_short Seemingly Harmless Differentiated Thyroid Carcinoma Presenting as Bone Metastasis
title_sort seemingly harmless differentiated thyroid carcinoma presenting as bone metastasis
url http://dx.doi.org/10.1155/2018/8749075
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