The intracellular bacterium Orientia tsutsugamushi uses the autotransporter ScaC to activate BICD adaptors for dynein-based motility

Abstract The intracellular bacterium Orientia tsutsugamushi relies on the microtubule cytoskeleton and the motor protein dynein to traffic to the perinuclear region within infected cells. However, it remains unclear how the bacterium is coupled to the dynein machinery and how transport is regulated....

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Bibliographic Details
Main Authors: Giulia Manigrasso, Kittirat Saharat, Panjaporn Chaichana, Chitrasak Kullapanich, Sharanjeet Atwal, Jerome Boulanger, Tomos E. Morgan, Holger Kramer, Jeanne Salje, Andrew P. Carter
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61105-5
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