RNAi epimutations conferring antifungal drug resistance are inheritable
Abstract Epimutations modify gene expression and lead to phenotypic variation while the encoding DNA sequence remains unchanged. Epimutations mediated by RNA interference (RNAi) and/or chromatin modifications can confer antifungal drug resistance and may impact virulence traits in fungi. However, wh...
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| Main Authors: | Carlos Pérez-Arques, María Isabel Navarro-Mendoza, Ziyan Xu, Grit Walther, Joseph Heitman |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-08-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-62572-6 |
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