Synthesis, Characterisation, Biological Evaluation and In Silico Studies of Quinoline–1,2,3-Triazole–Anilines as Potential Antitubercular and Anti-HIV Agents

Synthesis, Characterisation, Biological Evaluation and In Silico Studies of Quinoline–1,2,3-Triazole–Anilines as Potential Antitubercular and Anti-HIV Agents

HIV/AIDS and <i>Mycobacterial tuberculosis</i> (<i>Mtb</i>) are the leading cause of deaths worldwide. Thus, better medicaments are required to manage these diseases. Quinolines have shown great potential due to their broad spectrum of biological activity. Thus, quinoline–1,2...

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Bibliographic Details
Main Authors: Snethemba S. Magwaza, Darian Naidu, Oluwatoba E. Oyeneyin, Sibusiso Senzani, Nompumelelo P. Mkhwanazi, Matshawandile Tukulula
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Molecules
Subjects:
quinoline–1,2,3-triazole–anilines
click reaction
HIV-1 subtype B
molecular docking
DFT (density  functional theory)
Online Access:https://www.mdpi.com/1420-3049/30/10/2119
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