Seroprevalence of human cystic echinococcosis in individuals occupationally exposed to Canidae in Central Iran: A case-control study
Echinococcus granulosus is a widespread zoonotic tapeworm that causes human cystic echinococcosis. Human CE, transmitted via dogs or Canidae feces, poses a public health challenge and exemplifies the One Health Theory. This survey was conducted to determine the seroprevalence of CE in individuals oc...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-06-01
|
| Series: | Food and Waterborne Parasitology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405676625000101 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849435291397390336 |
|---|---|
| author | Seyed Hossein Hejazi Reza Kalantari Seyed Mahmoud Mousavi Marzieh Safari Zahra Ghayour Zary Nokhodian Mahsa Esmaeilifallah |
| author_facet | Seyed Hossein Hejazi Reza Kalantari Seyed Mahmoud Mousavi Marzieh Safari Zahra Ghayour Zary Nokhodian Mahsa Esmaeilifallah |
| author_sort | Seyed Hossein Hejazi |
| collection | DOAJ |
| description | Echinococcus granulosus is a widespread zoonotic tapeworm that causes human cystic echinococcosis. Human CE, transmitted via dogs or Canidae feces, poses a public health challenge and exemplifies the One Health Theory. This survey was conducted to determine the seroprevalence of CE in individuals occupationally exposed (IOE) to dogs, livestock wool, and contaminated soil due to egg shedding from dogs/Canidae in industrial slaughterhouses and livestock fields, compared to a healthy control group in Isfahan province, central Iran. In a case-control study, 401 sera from IOE, including slaughterhouse workers, animal husbandry unit workers, wool industry workers, farm workers, livestock farmers, butchers, and veterinarians in the case group, were matched with 401 archived samples from the general population. All 802 samples were tested for echinococcosis IgG using ELISA. Out of 802 sera, 7 (0.9 %) tested positive for Echinococcus IgG. The seroprevalence in the IOE and control groups was 1.2 % (5/401) and 0.5 % (2/401), respectively. Although there was a 2.5-fold estimated risk of CE in IOE compared to the control group, this was not statistically significant. Based on the current study's findings, the overall seroprevalence of CE in the Isfahan area is similar to that of other regions in Iran. |
| format | Article |
| id | doaj-art-e9fa7af6936a4dc89c1752ddd6b3c8b1 |
| institution | Kabale University |
| issn | 2405-6766 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Food and Waterborne Parasitology |
| spelling | doaj-art-e9fa7af6936a4dc89c1752ddd6b3c8b12025-08-20T03:26:20ZengElsevierFood and Waterborne Parasitology2405-67662025-06-0139e0026310.1016/j.fawpar.2025.e00263Seroprevalence of human cystic echinococcosis in individuals occupationally exposed to Canidae in Central Iran: A case-control studySeyed Hossein Hejazi0Reza Kalantari1Seyed Mahmoud Mousavi2Marzieh Safari3Zahra Ghayour4Zary Nokhodian5Mahsa Esmaeilifallah6Department. of Parasitology and Mycology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IranDepartment. of Parasitology and Mycology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran; Student Research Committee, Isfahan University of Medical Sciences, Isfahan, IranDepartment. of Parasitology and Mycology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IranDepartment of Medical Laboratory Sciences, Urmia Branch, Islamic Azad University, Urmia, IranDepartment. of Parasitology and Mycology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IranInfectious Diseases and Tropical Medicine Research Centre, Isfahan University of Medical Sciences, Isfahan, IranDepartment. of Parasitology and Mycology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran; Corresponding author at: Department of Parasitology and Mycology, School of Medicine, Isfahan University of Medical Sciences, Hezar Jerib St., Isfahan 8174673461, Iran.Echinococcus granulosus is a widespread zoonotic tapeworm that causes human cystic echinococcosis. Human CE, transmitted via dogs or Canidae feces, poses a public health challenge and exemplifies the One Health Theory. This survey was conducted to determine the seroprevalence of CE in individuals occupationally exposed (IOE) to dogs, livestock wool, and contaminated soil due to egg shedding from dogs/Canidae in industrial slaughterhouses and livestock fields, compared to a healthy control group in Isfahan province, central Iran. In a case-control study, 401 sera from IOE, including slaughterhouse workers, animal husbandry unit workers, wool industry workers, farm workers, livestock farmers, butchers, and veterinarians in the case group, were matched with 401 archived samples from the general population. All 802 samples were tested for echinococcosis IgG using ELISA. Out of 802 sera, 7 (0.9 %) tested positive for Echinococcus IgG. The seroprevalence in the IOE and control groups was 1.2 % (5/401) and 0.5 % (2/401), respectively. Although there was a 2.5-fold estimated risk of CE in IOE compared to the control group, this was not statistically significant. Based on the current study's findings, the overall seroprevalence of CE in the Isfahan area is similar to that of other regions in Iran.http://www.sciencedirect.com/science/article/pii/S2405676625000101AbattoirCystic echinococcosisOccupational exposureRisk factorsSeroprevalenceZoonoses |
| spellingShingle | Seyed Hossein Hejazi Reza Kalantari Seyed Mahmoud Mousavi Marzieh Safari Zahra Ghayour Zary Nokhodian Mahsa Esmaeilifallah Seroprevalence of human cystic echinococcosis in individuals occupationally exposed to Canidae in Central Iran: A case-control study Food and Waterborne Parasitology Abattoir Cystic echinococcosis Occupational exposure Risk factors Seroprevalence Zoonoses |
| title | Seroprevalence of human cystic echinococcosis in individuals occupationally exposed to Canidae in Central Iran: A case-control study |
| title_full | Seroprevalence of human cystic echinococcosis in individuals occupationally exposed to Canidae in Central Iran: A case-control study |
| title_fullStr | Seroprevalence of human cystic echinococcosis in individuals occupationally exposed to Canidae in Central Iran: A case-control study |
| title_full_unstemmed | Seroprevalence of human cystic echinococcosis in individuals occupationally exposed to Canidae in Central Iran: A case-control study |
| title_short | Seroprevalence of human cystic echinococcosis in individuals occupationally exposed to Canidae in Central Iran: A case-control study |
| title_sort | seroprevalence of human cystic echinococcosis in individuals occupationally exposed to canidae in central iran a case control study |
| topic | Abattoir Cystic echinococcosis Occupational exposure Risk factors Seroprevalence Zoonoses |
| url | http://www.sciencedirect.com/science/article/pii/S2405676625000101 |
| work_keys_str_mv | AT seyedhosseinhejazi seroprevalenceofhumancysticechinococcosisinindividualsoccupationallyexposedtocanidaeincentraliranacasecontrolstudy AT rezakalantari seroprevalenceofhumancysticechinococcosisinindividualsoccupationallyexposedtocanidaeincentraliranacasecontrolstudy AT seyedmahmoudmousavi seroprevalenceofhumancysticechinococcosisinindividualsoccupationallyexposedtocanidaeincentraliranacasecontrolstudy AT marziehsafari seroprevalenceofhumancysticechinococcosisinindividualsoccupationallyexposedtocanidaeincentraliranacasecontrolstudy AT zahraghayour seroprevalenceofhumancysticechinococcosisinindividualsoccupationallyexposedtocanidaeincentraliranacasecontrolstudy AT zarynokhodian seroprevalenceofhumancysticechinococcosisinindividualsoccupationallyexposedtocanidaeincentraliranacasecontrolstudy AT mahsaesmaeilifallah seroprevalenceofhumancysticechinococcosisinindividualsoccupationallyexposedtocanidaeincentraliranacasecontrolstudy |