Systemic therapy for advanced cholangiocarcinoma: divergences in global guidelines and regional clinical implementation

Cholangiocarcinoma (CCA) is a group of malignant tumors arising from the biliary epithelium, with systemic therapy serving as the primary treatment approach for patients with advanced disease. In recent years, advances in molecular classification and targeted therapy have led to rapid updates in tre...

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Main Author: LI Chun, MA Zuyi, SUN Jia, LI Binglu
Format: Article
Language:zho
Published: Editorial Office of Journal of Surgery Concepts & Practice 2025-03-01
Series:Waike lilun yu shijian
Subjects:
Online Access:https://www.qk.sjtu.edu.cn/jscp/fileup/1007-9610/PDF/1751876366055-475213852.pdf
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author LI Chun, MA Zuyi, SUN Jia, LI Binglu
author_facet LI Chun, MA Zuyi, SUN Jia, LI Binglu
author_sort LI Chun, MA Zuyi, SUN Jia, LI Binglu
collection DOAJ
description Cholangiocarcinoma (CCA) is a group of malignant tumors arising from the biliary epithelium, with systemic therapy serving as the primary treatment approach for patients with advanced disease. In recent years, advances in molecular classification and targeted therapy have led to rapid updates in treatment guidelines for CCA. This review summarized recent progress in systemic treatment strategies for advanced CCA and the relevant recommendations in both international and domestic guidelines, aiming to provide evidence-based references for clinical management and decision-making in patients with CCA.
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institution Kabale University
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publisher Editorial Office of Journal of Surgery Concepts & Practice
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spelling doaj-art-e9fa4a10752c43239d56fd2dad12e1292025-08-20T03:33:27ZzhoEditorial Office of Journal of Surgery Concepts & PracticeWaike lilun yu shijian1007-96102025-03-013029310010.16139/j.1007-9610.2025.02.01Systemic therapy for advanced cholangiocarcinoma: divergences in global guidelines and regional clinical implementationLI Chun, MA Zuyi, SUN Jia, LI Binglu0Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100005, ChinaCholangiocarcinoma (CCA) is a group of malignant tumors arising from the biliary epithelium, with systemic therapy serving as the primary treatment approach for patients with advanced disease. In recent years, advances in molecular classification and targeted therapy have led to rapid updates in treatment guidelines for CCA. This review summarized recent progress in systemic treatment strategies for advanced CCA and the relevant recommendations in both international and domestic guidelines, aiming to provide evidence-based references for clinical management and decision-making in patients with CCA.https://www.qk.sjtu.edu.cn/jscp/fileup/1007-9610/PDF/1751876366055-475213852.pdf|cholangiocarcinoma(cca)|systemic therapy|chemotherapy|immunotherapy|molecular targeted therapy
spellingShingle LI Chun, MA Zuyi, SUN Jia, LI Binglu
Systemic therapy for advanced cholangiocarcinoma: divergences in global guidelines and regional clinical implementation
Waike lilun yu shijian
|cholangiocarcinoma(cca)|systemic therapy|chemotherapy|immunotherapy|molecular targeted therapy
title Systemic therapy for advanced cholangiocarcinoma: divergences in global guidelines and regional clinical implementation
title_full Systemic therapy for advanced cholangiocarcinoma: divergences in global guidelines and regional clinical implementation
title_fullStr Systemic therapy for advanced cholangiocarcinoma: divergences in global guidelines and regional clinical implementation
title_full_unstemmed Systemic therapy for advanced cholangiocarcinoma: divergences in global guidelines and regional clinical implementation
title_short Systemic therapy for advanced cholangiocarcinoma: divergences in global guidelines and regional clinical implementation
title_sort systemic therapy for advanced cholangiocarcinoma divergences in global guidelines and regional clinical implementation
topic |cholangiocarcinoma(cca)|systemic therapy|chemotherapy|immunotherapy|molecular targeted therapy
url https://www.qk.sjtu.edu.cn/jscp/fileup/1007-9610/PDF/1751876366055-475213852.pdf
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