Systemic therapy for advanced cholangiocarcinoma: divergences in global guidelines and regional clinical implementation
Cholangiocarcinoma (CCA) is a group of malignant tumors arising from the biliary epithelium, with systemic therapy serving as the primary treatment approach for patients with advanced disease. In recent years, advances in molecular classification and targeted therapy have led to rapid updates in tre...
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| Format: | Article |
| Language: | zho |
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Editorial Office of Journal of Surgery Concepts & Practice
2025-03-01
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| Series: | Waike lilun yu shijian |
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| Online Access: | https://www.qk.sjtu.edu.cn/jscp/fileup/1007-9610/PDF/1751876366055-475213852.pdf |
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| _version_ | 1849415595364188160 |
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| author | LI Chun, MA Zuyi, SUN Jia, LI Binglu |
| author_facet | LI Chun, MA Zuyi, SUN Jia, LI Binglu |
| author_sort | LI Chun, MA Zuyi, SUN Jia, LI Binglu |
| collection | DOAJ |
| description | Cholangiocarcinoma (CCA) is a group of malignant tumors arising from the biliary epithelium, with systemic therapy serving as the primary treatment approach for patients with advanced disease. In recent years, advances in molecular classification and targeted therapy have led to rapid updates in treatment guidelines for CCA. This review summarized recent progress in systemic treatment strategies for advanced CCA and the relevant recommendations in both international and domestic guidelines, aiming to provide evidence-based references for clinical management and decision-making in patients with CCA. |
| format | Article |
| id | doaj-art-e9fa4a10752c43239d56fd2dad12e129 |
| institution | Kabale University |
| issn | 1007-9610 |
| language | zho |
| publishDate | 2025-03-01 |
| publisher | Editorial Office of Journal of Surgery Concepts & Practice |
| record_format | Article |
| series | Waike lilun yu shijian |
| spelling | doaj-art-e9fa4a10752c43239d56fd2dad12e1292025-08-20T03:33:27ZzhoEditorial Office of Journal of Surgery Concepts & PracticeWaike lilun yu shijian1007-96102025-03-013029310010.16139/j.1007-9610.2025.02.01Systemic therapy for advanced cholangiocarcinoma: divergences in global guidelines and regional clinical implementationLI Chun, MA Zuyi, SUN Jia, LI Binglu0Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100005, ChinaCholangiocarcinoma (CCA) is a group of malignant tumors arising from the biliary epithelium, with systemic therapy serving as the primary treatment approach for patients with advanced disease. In recent years, advances in molecular classification and targeted therapy have led to rapid updates in treatment guidelines for CCA. This review summarized recent progress in systemic treatment strategies for advanced CCA and the relevant recommendations in both international and domestic guidelines, aiming to provide evidence-based references for clinical management and decision-making in patients with CCA.https://www.qk.sjtu.edu.cn/jscp/fileup/1007-9610/PDF/1751876366055-475213852.pdf|cholangiocarcinoma(cca)|systemic therapy|chemotherapy|immunotherapy|molecular targeted therapy |
| spellingShingle | LI Chun, MA Zuyi, SUN Jia, LI Binglu Systemic therapy for advanced cholangiocarcinoma: divergences in global guidelines and regional clinical implementation Waike lilun yu shijian |cholangiocarcinoma(cca)|systemic therapy|chemotherapy|immunotherapy|molecular targeted therapy |
| title | Systemic therapy for advanced cholangiocarcinoma: divergences in global guidelines and regional clinical implementation |
| title_full | Systemic therapy for advanced cholangiocarcinoma: divergences in global guidelines and regional clinical implementation |
| title_fullStr | Systemic therapy for advanced cholangiocarcinoma: divergences in global guidelines and regional clinical implementation |
| title_full_unstemmed | Systemic therapy for advanced cholangiocarcinoma: divergences in global guidelines and regional clinical implementation |
| title_short | Systemic therapy for advanced cholangiocarcinoma: divergences in global guidelines and regional clinical implementation |
| title_sort | systemic therapy for advanced cholangiocarcinoma divergences in global guidelines and regional clinical implementation |
| topic | |cholangiocarcinoma(cca)|systemic therapy|chemotherapy|immunotherapy|molecular targeted therapy |
| url | https://www.qk.sjtu.edu.cn/jscp/fileup/1007-9610/PDF/1751876366055-475213852.pdf |
| work_keys_str_mv | AT lichunmazuyisunjialibinglu systemictherapyforadvancedcholangiocarcinomadivergencesinglobalguidelinesandregionalclinicalimplementation |