Anticancer Effect of Ascidian Aplidium Species Extract against Ovarian and Breast Cancer Cell Lines
Introduction: Cancer continues to pose a significant challenge in the field of medicine, demanding innovative approaches and novel therapeutic avenues for effective treatment. Within this landscape, the exploration of natural compounds derived from marine organisms has garnered attention for their p...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2025-06-01
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| Series: | Journal of Pharmacy and Bioallied Sciences |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/jpbs.jpbs_288_25 |
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| author | Gaurav Makrand Thoke Palati Sinduja Kumaravel Kaliaperumal Swati Gandham Subhashri Rajasekar Pavithra Murugesan |
| author_facet | Gaurav Makrand Thoke Palati Sinduja Kumaravel Kaliaperumal Swati Gandham Subhashri Rajasekar Pavithra Murugesan |
| author_sort | Gaurav Makrand Thoke |
| collection | DOAJ |
| description | Introduction:
Cancer continues to pose a significant challenge in the field of medicine, demanding innovative approaches and novel therapeutic avenues for effective treatment. Within this landscape, the exploration of natural compounds derived from marine organisms has garnered attention for their potential anti-cancer properties.
Aim:
Our present study aims to evaluate the pharmacological effect of Aplidium species in terms of anti-cancer properties which are assessed through biochemical methods.
Materials and Methods:
The sample was collected from the Thiruchender coastal areas. It was then washed and extracted with methanol which then was used for biological screening against two cancer strains, namely, MCF-7 (Breast cancer cell line) and A2780 (Ovarian Cancer cell line).
Conclusion:
Alpidium sp extract has significant anticancer effect against two different cancer cell lines when compared to standard drugs. |
| format | Article |
| id | doaj-art-e9efc9cc21954df9be93afb4588069d6 |
| institution | Kabale University |
| issn | 0976-4879 0975-7406 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Pharmacy and Bioallied Sciences |
| spelling | doaj-art-e9efc9cc21954df9be93afb4588069d62025-08-20T03:31:35ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0976-48790975-74062025-06-0117Suppl 2S1839S184110.4103/jpbs.jpbs_288_25Anticancer Effect of Ascidian Aplidium Species Extract against Ovarian and Breast Cancer Cell LinesGaurav Makrand ThokePalati SindujaKumaravel KaliaperumalSwati GandhamSubhashri RajasekarPavithra MurugesanIntroduction: Cancer continues to pose a significant challenge in the field of medicine, demanding innovative approaches and novel therapeutic avenues for effective treatment. Within this landscape, the exploration of natural compounds derived from marine organisms has garnered attention for their potential anti-cancer properties. Aim: Our present study aims to evaluate the pharmacological effect of Aplidium species in terms of anti-cancer properties which are assessed through biochemical methods. Materials and Methods: The sample was collected from the Thiruchender coastal areas. It was then washed and extracted with methanol which then was used for biological screening against two cancer strains, namely, MCF-7 (Breast cancer cell line) and A2780 (Ovarian Cancer cell line). Conclusion: Alpidium sp extract has significant anticancer effect against two different cancer cell lines when compared to standard drugs.https://journals.lww.com/10.4103/jpbs.jpbs_288_25a2780 cell lineaplidium speciesmcf-7 cell linenovel changes |
| spellingShingle | Gaurav Makrand Thoke Palati Sinduja Kumaravel Kaliaperumal Swati Gandham Subhashri Rajasekar Pavithra Murugesan Anticancer Effect of Ascidian Aplidium Species Extract against Ovarian and Breast Cancer Cell Lines Journal of Pharmacy and Bioallied Sciences a2780 cell line aplidium species mcf-7 cell line novel changes |
| title | Anticancer Effect of Ascidian Aplidium Species Extract against Ovarian and Breast Cancer Cell Lines |
| title_full | Anticancer Effect of Ascidian Aplidium Species Extract against Ovarian and Breast Cancer Cell Lines |
| title_fullStr | Anticancer Effect of Ascidian Aplidium Species Extract against Ovarian and Breast Cancer Cell Lines |
| title_full_unstemmed | Anticancer Effect of Ascidian Aplidium Species Extract against Ovarian and Breast Cancer Cell Lines |
| title_short | Anticancer Effect of Ascidian Aplidium Species Extract against Ovarian and Breast Cancer Cell Lines |
| title_sort | anticancer effect of ascidian aplidium species extract against ovarian and breast cancer cell lines |
| topic | a2780 cell line aplidium species mcf-7 cell line novel changes |
| url | https://journals.lww.com/10.4103/jpbs.jpbs_288_25 |
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