The role of fructose-1,6-bisphosphatase 1 on regulating the cancer progression and drug resistance

Abstract Fructose-1,6-bisphosphatase 1 (FBP1) is the enzyme that limits the process of gluconeogenesis as it facilitates the hydrolysis of fructose-1,6-bisphosphate(F-1,6-BP) to produce fructose-6-phosphate(F6P) and inorganic phosphate. Gluconeogenesis is the production of glucose from small carbohy...

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Bibliographic Details
Main Authors: Mengmeng Wang, Xiaoju Huang, Dan Zhang, Yisan Liu, Pian Liu
Format: Article
Language:English
Published: Springer 2025-03-01
Series:Discover Oncology
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Online Access:https://doi.org/10.1007/s12672-025-02112-2
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