Circadian disruption impairs Leydig cell maturation and reproductive development in male rats

Abstract Circadian desynchrony, caused by a misalignment between the internal biological clock and environmental light cues, is increasingly prevalent in adolescents due to irregular light exposure and social pressures. However, its impact on reproductive maturation remains poorly understood. In thi...

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Bibliographic Details
Main Authors: Dijana Z. Travicic, Dejan Miljkovic, Silvana A. Andric, Tatjana S. Kostic
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Reproductive Biology and Endocrinology
Online Access:https://doi.org/10.1186/s12958-025-01440-w
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