Transcripts derived from AmnSINE1 repetitive sequences are depleted in the cortex of autism spectrum disorder patients

Transcripts derived from AmnSINE1 repetitive sequences are depleted in the cortex of autism spectrum disorder patients

AimsAutism spectrum disorder (ASD) is a brain developmental disability with a not-fully clarified etiogenesis. Current ASD research largely focuses on coding regions of the genome, but up to date much less is known about the contribution of non-coding elements to ASD risk. The non-coding genome is l...

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Bibliographic Details
Main Authors: Nicolina Sciaraffa, Daniele Santoni, Andrea Li Greci, Swonild Ilenia Genovese, Claudia Coronnello, Walter Arancio
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Bioinformatics
Subjects:
autism spectrum disorder
repetitive sequences
neurogenesis
microRNA
embryonic development
autistic disorder
Online Access:https://www.frontiersin.org/articles/10.3389/fbinf.2025.1532981/full
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