Investigating the impact of non-standard positioning on the accuracy of skull tracking algorithms using dual-panel imaging systems

ObjectiveThis study investigates the impact of non-standard positioning on the accuracy of 6D-skull tracking using dual-panel imaging systems. It explores whether positioning patients’ heads at various angles during intracranial lesion treatment affects the accuracy of the CyberKnife 6D-skull tracki...

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Main Authors: He Huang, Lian Zhang, Yunfei Bian, Yang Dong, Hongyu Lin, Hui Xu, Ying Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1458158/full
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author He Huang
Lian Zhang
Yunfei Bian
Yang Dong
Hongyu Lin
Hui Xu
Ying Li
author_facet He Huang
Lian Zhang
Yunfei Bian
Yang Dong
Hongyu Lin
Hui Xu
Ying Li
author_sort He Huang
collection DOAJ
description ObjectiveThis study investigates the impact of non-standard positioning on the accuracy of 6D-skull tracking using dual-panel imaging systems. It explores whether positioning patients’ heads at various angles during intracranial lesion treatment affects the accuracy of the CyberKnife 6D-skull tracking system.Materials and methodsA heterogeneous density skull phantom was used to simulate various patient skull positioning angles. To accurately compare 6D-skull tracking and fiducial tracking, their center coordinates were pre-set to be identical in the treatment plan. The phantom was positioned using fiducial tracking, and the offset value recorded. The system was then switched to 6D-skull tracking to observe the corresponding offset. The difference between the two tracking methods was calculated, and a paired-sample T-test was conducted to assess statistical significance across different angles. Additionally, the gamma passing rate (criteria: 3%/3mm) was employed to quantitatively delineate dosimetric disparities attributable to positional variations.ResultsPaired sample T-tests on the deviations between rotational and translational parameters of fiducial tracking and skull tracking under identical conditions revealed no statistically significant differences between the methods across all selected angles. The minimal deviations and lack of statistical significance demonstrate that both tracking methods are equivalent in skull positioning. Furthermore, the gamma passing rate analysis showed that in all tested conditions, the rates exceeded 95%, which aligns with clinical requirements. This high passing rate indicates a high degree of dosimetric accuracy and consistency between the two tracking methods, providing robust assurance of treatment precision in skull positioning.ConclusionSince fiducial tracking is not affected by patient or phantom positioning, this study compares the registration results of 6D-skull tracking with fiducial tracking under the same conditions. The results show minimal deviations and no statistically significant differences, indicating that 6D-skull tracking is not dependent on the skull’s positioning angle. Furthermore, the gamma passing rate analysis was conducted to quantitatively assess the dosimetric differences arising from variations in patient positioning. Our results demonstrated that under all tested conditions, the gamma passing rates exceeded the clinically accepted threshold of 95%, confirming the clinical adequacy of both tracking methods in maintaining treatment precision. In clinical practice, patients do not need to maintain a strict supine position; the algorithm can accurately perform registration even if patients need to rotate their heads or lie prone. Clinical recommendations should prioritize patient comfort and safety without imposing overly strict requirements.
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spelling doaj-art-e9c9b6095a384469a8ab9650f684826e2025-08-20T01:52:48ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2024-11-011410.3389/fonc.2024.14581581458158Investigating the impact of non-standard positioning on the accuracy of skull tracking algorithms using dual-panel imaging systemsHe Huang0Lian Zhang1Yunfei Bian2Yang Dong3Hongyu Lin4Hui Xu5Ying Li6Department of Oncology, The First Hospital of Hebei Medical University, Shijiazhuang, ChinaDepartment of Oncology, The First Hospital of Hebei Medical University, Shijiazhuang, ChinaDepartment of Oncology, The First Hospital of Hebei Medical University, Shijiazhuang, ChinaDepartment of Radiation Oncology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin’s Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, ChinaDepartment of Oncology, The First Hospital of Hebei Medical University, Shijiazhuang, ChinaDepartment of Oncology, The First Hospital of Hebei Medical University, Shijiazhuang, ChinaDepartment of Oncology, The First Hospital of Hebei Medical University, Shijiazhuang, ChinaObjectiveThis study investigates the impact of non-standard positioning on the accuracy of 6D-skull tracking using dual-panel imaging systems. It explores whether positioning patients’ heads at various angles during intracranial lesion treatment affects the accuracy of the CyberKnife 6D-skull tracking system.Materials and methodsA heterogeneous density skull phantom was used to simulate various patient skull positioning angles. To accurately compare 6D-skull tracking and fiducial tracking, their center coordinates were pre-set to be identical in the treatment plan. The phantom was positioned using fiducial tracking, and the offset value recorded. The system was then switched to 6D-skull tracking to observe the corresponding offset. The difference between the two tracking methods was calculated, and a paired-sample T-test was conducted to assess statistical significance across different angles. Additionally, the gamma passing rate (criteria: 3%/3mm) was employed to quantitatively delineate dosimetric disparities attributable to positional variations.ResultsPaired sample T-tests on the deviations between rotational and translational parameters of fiducial tracking and skull tracking under identical conditions revealed no statistically significant differences between the methods across all selected angles. The minimal deviations and lack of statistical significance demonstrate that both tracking methods are equivalent in skull positioning. Furthermore, the gamma passing rate analysis showed that in all tested conditions, the rates exceeded 95%, which aligns with clinical requirements. This high passing rate indicates a high degree of dosimetric accuracy and consistency between the two tracking methods, providing robust assurance of treatment precision in skull positioning.ConclusionSince fiducial tracking is not affected by patient or phantom positioning, this study compares the registration results of 6D-skull tracking with fiducial tracking under the same conditions. The results show minimal deviations and no statistically significant differences, indicating that 6D-skull tracking is not dependent on the skull’s positioning angle. Furthermore, the gamma passing rate analysis was conducted to quantitatively assess the dosimetric differences arising from variations in patient positioning. Our results demonstrated that under all tested conditions, the gamma passing rates exceeded the clinically accepted threshold of 95%, confirming the clinical adequacy of both tracking methods in maintaining treatment precision. In clinical practice, patients do not need to maintain a strict supine position; the algorithm can accurately perform registration even if patients need to rotate their heads or lie prone. Clinical recommendations should prioritize patient comfort and safety without imposing overly strict requirements.https://www.frontiersin.org/articles/10.3389/fonc.2024.1458158/fullCyberKnifeskull trackingnon-standard positioningdual-panel imaging systemradiotherapy
spellingShingle He Huang
Lian Zhang
Yunfei Bian
Yang Dong
Hongyu Lin
Hui Xu
Ying Li
Investigating the impact of non-standard positioning on the accuracy of skull tracking algorithms using dual-panel imaging systems
Frontiers in Oncology
CyberKnife
skull tracking
non-standard positioning
dual-panel imaging system
radiotherapy
title Investigating the impact of non-standard positioning on the accuracy of skull tracking algorithms using dual-panel imaging systems
title_full Investigating the impact of non-standard positioning on the accuracy of skull tracking algorithms using dual-panel imaging systems
title_fullStr Investigating the impact of non-standard positioning on the accuracy of skull tracking algorithms using dual-panel imaging systems
title_full_unstemmed Investigating the impact of non-standard positioning on the accuracy of skull tracking algorithms using dual-panel imaging systems
title_short Investigating the impact of non-standard positioning on the accuracy of skull tracking algorithms using dual-panel imaging systems
title_sort investigating the impact of non standard positioning on the accuracy of skull tracking algorithms using dual panel imaging systems
topic CyberKnife
skull tracking
non-standard positioning
dual-panel imaging system
radiotherapy
url https://www.frontiersin.org/articles/10.3389/fonc.2024.1458158/full
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