Microgliosis in the Spinal Dorsal Horn Early After Peripheral Nerve Injury Is Associated with Damage to Primary Afferent Aβ-Fibers

Microgliosis in the Spinal Dorsal Horn Early After Peripheral Nerve Injury Is Associated with Damage to Primary Afferent Aβ-Fibers

Neuropathic pain results from a lesion or disease affecting the somatosensory nervous system. Injury to primary afferent nerves leads to microgliosis in the spinal dorsal horn (SDH), which plays a crucial role in developing neuropathic pain. Within the SDH, primary afferent fibers broadly project, a...

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Bibliographic Details
Main Authors: Yuto Shibata, Yuki Matsumoto, Keita Kohno, Yasuharu Nakashima, Makoto Tsuda
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Cells
Subjects:
microglia
primary afferents
Aβ-fibers
C-fibers
peripheral nerve injury
spinal dorsal horn
Online Access:https://www.mdpi.com/2073-4409/14/9/666
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